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胸主动脉腔内修复术后全身免疫炎症指数对 B 型主动脉夹层患者的预后价值。

Prognostic Value of the Systemic Immune Inflammation Index after Thoracic Endovascular Aortic Repair in Patients with Type B Aortic Dissection.

机构信息

Department of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China.

Vascular Surgery Institute of Fudan University, Shanghai 200032, China.

出版信息

Dis Markers. 2023 Feb 17;2023:2126882. doi: 10.1155/2023/2126882. eCollection 2023.

Abstract

The study aimed at investigating the association between postoperative inflammatory scores and aorta-related adverse events (AAEs) after thoracic endovascular aortic repair (TEVAR) for patients with type B aortic dissection (TBAD). This single-centre, retrospective cohort included all patients who underwent TEVAR for TBAD between November 2016 and November 2020 at a university hospital. The risk factors for AAEs were analyzed by Cox proportional hazards model regression. Prediction accuracy was assessed using the area under the receiver operating characteristic curves. This study included 186 patients with a mean age of 58.5 years and a median follow-up period of 26 months. A total of 68 patients developed AAEs. Age and postoperative systemic immune inflammation index (SII) (>2893) were associated with post-TEVAR AAEs (hazard ratio (HR) 1.03, = 0.003; HR 1.88, = 0.043, respectively). Increased postoperative SII and age are independent risk factors for AAE post-TEVAR in patients with TBAD.

摘要

本研究旨在探讨胸主动脉腔内修复术(TEVAR)治疗 B 型主动脉夹层(TBAD)患者术后炎症评分与主动脉相关不良事件(AAE)之间的关系。该单中心回顾性队列纳入了 2016 年 11 月至 2020 年 11 月期间在一所大学医院接受 TEVAR 治疗的所有 TBAD 患者。采用 Cox 比例风险模型回归分析 AAE 的危险因素。通过受试者工作特征曲线下面积评估预测准确性。本研究共纳入 186 例患者,平均年龄为 58.5 岁,中位随访时间为 26 个月。共有 68 例患者发生 AAE。年龄和术后全身免疫炎症指数(SII)(>2893)与 TEVAR 后 AAE 相关(风险比(HR)1.03, = 0.003;HR 1.88, = 0.043)。术后 SII 升高和年龄是 TBAD 患者 TEVAR 后发生 AAE 的独立危险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9942/9957628/d9cc0c571c3e/DM2023-2126882.001.jpg

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