Siamisang Aobakwe Betty, Gezmu Alemayehu M, Slone Jeremy S, Gabaitiri Lesego, David Thuso, Phetogo Bathusi, Joel Dipesalema
University of Botswana, Gaborone, Botswana.
St Jude Children's Research Hospital, Memphis, TN, USA.
Glob Pediatr Health. 2023 Feb 20;10:2333794X231156059. doi: 10.1177/2333794X231156059. eCollection 2023.
Anemia is a global health concern and has been associated with long term cognitive and behavioral adverse effects. A cross sectional study was conducted to determine the prevalence of and risk factors for anemia in infants and children between 6 months to 5 years of age admitted to a tertiary hospital in Botswana. Baseline full blood count of every patient admitted during the study period was assessed to determine if anemia was present. Data were collected from patient's medical inpatient chart, electronic medical record (Integrated Patient Management System (IPMS)), and through interviewing parents and caregivers. Multivariate logistic regression model was used to identify risk factors of anemia. A total of 250 patients were included in the study. Prevalence of anemia in this cohort was 42.8%. There were 145 (58%) males. Of the patients with anemia, 56.1%, 39.2%, and 4.7% had mild, moderate, and severe anemia, respectively. Microcytic anemia consistent with iron deficiency was identified in 61 (57%) patients. Age was the only independent predictor of anemia. Children aged 24 months and more had a 50% lower risk of having anemia than their younger counterparts (odds ratio (OR) 0.52; 95% Confidence Interval (95% CI) 0.30 to 0.89). The findings of this study demonstrate anemia as a serious health concern in the pediatric population in Botswana.
贫血是一个全球性的健康问题,并且与长期的认知和行为不良影响相关。开展了一项横断面研究,以确定在博茨瓦纳一家三级医院就诊的6个月至5岁婴幼儿及儿童贫血的患病率和危险因素。对研究期间收治的每位患者的基线全血细胞计数进行评估,以确定是否存在贫血。数据从患者的住院病历、电子病历(综合患者管理系统(IPMS))中收集,并通过访谈父母和照料者获取。采用多变量逻辑回归模型来识别贫血的危险因素。该研究共纳入250名患者。该队列中贫血的患病率为42.8%。有145名(58%)男性。在贫血患者中,分别有56.1%、39.2%和4.7%患有轻度、中度和重度贫血。61名(57%)患者被诊断为与缺铁相符的小细胞性贫血。年龄是贫血的唯一独立预测因素。24个月及以上的儿童患贫血的风险比年龄较小的儿童低50%(比值比(OR)0.52;95%置信区间(95%CI)0.30至0.89)。本研究结果表明,贫血是博茨瓦纳儿科人群中一个严重的健康问题。