Department of Biomedical Science, School of Medicine, College of Medicine and Health Sciences, Wolkite University, Wolkite, Southern Ethiopia.
Department of Medical Laboratory Science, College of Medicine and Health Sciences, Wolkite University, Wolkite, Southern Ethiopia.
PLoS One. 2022 Apr 4;17(4):e0266089. doi: 10.1371/journal.pone.0266089. eCollection 2022.
Anemia is a condition in which the number of red blood cells is inadequate to meet the physiologic needs of the human body oxygen and it is highly prevalent among individuals with metabolic syndromes as a complication in turn speed up the progression and the number of adverse outcomes unless the proper measure is undertaken. Determination of anemia may play a major role in the management and early aversion of complications in an admitted patient with metabolic syndromes. Therefore, this study aimed to determine anemia and its associated factors among patients with admitted metabolic syndromes at Worabe Comprehensive Specialized hospital, Southern Ethiopia from March 1 to May 30, 2021.
An institutional-based cross-sectional study design was conducted on 324 adult patients admitted with metabolic syndromes. Structured questionnaires through face-to-face interviews and participants' medical records were used to collect information on determinants related to anemia. A blood sample was collected to determine hematological parameters, biochemical profile, and blood film preparation. Data were analyzed by SPSS version 22. Binary logistic regression analyses were done to identify factors associated with anemia. The p-value was set at <0.05 with a 95% confidence interval of the adjusted odds ratio.
A total of 324 admitted adult patients with metabolic syndromes were involved. The overall prevalence of anemia among study participants was 25.3% (95%CI: 20.7, 30.2), of which 52.4% had moderate anemia and 56% had microcytic types of anemia. Being alcoholic (AOR = 6.25, 95% CI: (3.05, 12.82)), obese (AOR = 3.34, 95% CI: (1.02, 11.21)), dyslipidemic (AOR = 2.06, 95% CI: (1.02, 4.17)), and diabetic (AOR = 2.61, 95%CI: (1.31, 5.21)) were significantly associated with anemia.
The prevalence of anemia among patients admitted with metabolic syndrome observed in this study was a moderate public health problem. Taking alcohol, being dyslipidemic, obese and diabetic was significantly associated with anemia. The finding of this study should be taken into consideration to implement preventive interventions on identified factors in study percipients. Taking fruit and vegetable, and promoting physical exercise, routine determination of fasting blood glucose and hemoglobin level in adult admitted metabolic syndromes patients were recommended to minimize the emergence of anemia.
贫血是一种由于人体对氧气的生理需求无法得到足够的红细胞数量而导致的病症，它在患有代谢综合征的个体中非常普遍，是一种并发症，会加速疾病的进展和不良后果的发生，除非采取适当的措施。确定贫血可能在患有代谢综合征的住院患者的管理和早期避免并发症方面发挥重要作用。因此，本研究旨在确定 2021 年 3 月 1 日至 5 月 30 日在埃塞俄比亚南部沃拉贝综合专科医院住院的代谢综合征患者中贫血及其相关因素。
这是一项在 324 名患有代谢综合征的成年住院患者中进行的基于机构的横断面研究。通过面对面访谈和参与者的病历使用结构化问卷收集与贫血相关的决定因素信息。采集血样以确定血液学参数、生化谱和血涂片准备。使用 SPSS 版本 22 进行数据分析。二项逻辑回归分析用于确定与贫血相关的因素。p 值设定为<0.05，调整后的优势比的 95%置信区间为 0.001。
共有 324 名患有代谢综合征的成年住院患者参与了这项研究。研究参与者中贫血的总体患病率为 25.3%（95%CI：20.7, 30.2），其中 52.4%为中度贫血，56%为小细胞性贫血。饮酒（AOR = 6.25，95%CI：（3.05, 12.82））、肥胖（AOR = 3.34，95%CI：（1.02, 11.21））、血脂异常（AOR = 2.06，95%CI：（1.02, 4.17））和糖尿病（AOR = 2.61，95%CI：（1.31, 5.21））与贫血显著相关。
本研究中观察到患有代谢综合征的住院患者中贫血的患病率是一个中度的公共卫生问题。饮酒、血脂异常、肥胖和糖尿病与贫血显著相关。应考虑到本研究的发现，以便在研究对象中针对确定的因素实施预防干预措施。建议在患有代谢综合征的成年住院患者中摄入水果和蔬菜，并促进体育锻炼，常规检测空腹血糖和血红蛋白水平，以尽量减少贫血的发生。
