Streck Joanna M, Regan Susan, Kalkhoran Sara, Kalagher Kelly M, Bearnot Benjamin, Gupta Priya S, Wakeman Sarah, Rigotti Nancy A
Tobacco Research and Treatment Center, Division of General Internal Medicine, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
Drug Alcohol Depend Rep. 2022 Jan 10;2:100023. doi: 10.1016/j.dadr.2022.100023. eCollection 2022 Mar.
Individuals with opioid use disorder (OUD) have a high prevalence of smoking and limited success quitting smoking with existing tools. There is ongoing debate about whether electronic cigarettes (e-cigarettes) may be a viable harm reduction strategy. We sought to determine the potential acceptability of e-cigarettes for cigarette harm reduction among individuals receiving medication treatment for opioid use disorder (MOUD) with buprenorphine. Among individuals receiving MOUD we investigated health harm perceptions of cigarettes, nicotine e-cigarettes, and nicotine replacement therapy (NRT), and perceptions of the helpfulness of e-cigarettes and NRT for quitting cigarettes.
Cross-sectional telephone survey conducted among adults in buprenorphine treatment at five community health centers in the Boston, MA metropolitan area from February to July 2020.
93% and 63% of participants rated cigarettes and e-cigarettes, respectively, as very or extremely harmful to health, and 62% rated NRT as not to slightly harmful to health. Over half (58%) rated cigarettes as more harmful than e-cigarettes; 65% and 83% perceived e-cigarettes and NRT, respectively, to be helpful for reducing/quitting cigarette use. In bivariate analyses, nicotine e-cigarette users, compared to nonusers, perceived e-cigarettes to be less harmful to health and more often rated e-cigarettes as helpful for reducing/quitting cigarette use (both <0.05).
This study suggests that Massachusetts patients receiving MOUD with buprenorphine have concerns about the health harms of e-cigarettes yet rate them as helpful tools for reducing or quitting cigarette smoking. Future research is needed to test the efficacy of e-cigarettes for cigarette harm reduction.
阿片类药物使用障碍(OUD)患者吸烟率很高,且使用现有工具戒烟成功率有限。关于电子烟是否可能是一种可行的减少危害策略,目前仍存在争议。我们试图确定电子烟在接受丁丙诺啡治疗阿片类药物使用障碍(MOUD)的个体中对减少香烟危害的潜在可接受性。在接受MOUD治疗的个体中,我们调查了对香烟、尼古丁电子烟和尼古丁替代疗法(NRT)的健康危害认知,以及对电子烟和NRT帮助戒烟的认知。
2020年2月至7月,在马萨诸塞州波士顿市区的五个社区卫生中心对接受丁丙诺啡治疗的成年人进行了横断面电话调查。
分别有93%和63%的参与者认为香烟和电子烟对健康非常或极其有害,62%的参与者认为NRT对健康无害至略有危害。超过一半(58%)的参与者认为香烟比电子烟危害更大;分别有65%和83%的参与者认为电子烟和NRT有助于减少/戒掉香烟使用。在双变量分析中,与非使用者相比,尼古丁电子烟使用者认为电子烟对健康危害较小,并且更常认为电子烟有助于减少/戒掉香烟使用(两者均P<0.05)。
本研究表明,马萨诸塞州接受丁丙诺啡MOUD治疗的患者担心电子烟对健康的危害,但认为它们是减少或戒掉吸烟的有用工具。需要进一步的研究来测试电子烟减少香烟危害的效果。