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[不同类型黄瘤病皮肤损害的脂质成分]

[Lipid composition of cutaneous lesions in different types of xanthomatosis].

作者信息

Ferrando J, Corominas Vilardell A

出版信息

Med Cutan Ibero Lat Am. 1977;5(6):415-24.

PMID:368463
Abstract

Twenty one specimens of cutaneous xanthomas from different types of hyperlipoproteinaemic and normolipidemic xanthomatosis were obtained and analyzed by thin layer chromatography. After separation and development, the areas were determinated by densitometry, and the results are given in percentages for each development. Acording to the results, the following data are of interest: -- Recents xanthomas have greater amount of lipids. -- Cholesterol esters (EC) are prevalent in xanthomas and in normal skin the triglycerides fraction. -- Monoenoic esters (EM) are prevalent on EC chromatography, like in normal skin. -- Finally, there are not significant variations between lipid composition of xanthomas in the different Xanthomatosis.

摘要

从不同类型的高脂蛋白血症性和正常血脂性黄瘤病中获取了21份皮肤黄瘤标本,并通过薄层色谱法进行分析。分离和展开后,通过光密度测定法测定面积,并给出每次展开的百分比结果。根据结果,以下数据值得关注:——近期黄瘤的脂质含量更高。——胆固醇酯(EC)在黄瘤中普遍存在,而在正常皮肤中甘油三酯部分占主导。——单烯酸酯(EM)在EC色谱上普遍存在,如同在正常皮肤中一样。——最后,不同黄瘤病中黄瘤的脂质组成之间没有显著差异。

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