Acıbadem Maslak Hospital, Clinic of Ophthalmology, İstanbul, Türkiye.
University of Health Sciences Türkiye Sultan 2. Abdulhamid Han Training and Research Hospital, Clinic of Ophthalmology, İstanbul, Türkiye.
Turk J Ophthalmol. 2023 Feb 24;53(1):58-66. doi: 10.4274/tjo.galenos.2022.53598.
This study presents the long-term clinical results of Argus II retinal prosthesis implantation in eyes with light perception and projection in 3 patients with end-stage retinitis pigmentosa. No conjunctival erosion, hypotony, or implant displacement was observed during postoperative follow-up. The electrical threshold values were lower in the macular region and higher close to the tack fixation region and peripherally. Optical coherence tomography scans showed fibrosis and retinoschisis formation at the retina-implant interface in two cases. This was attributed to mechanical and electrical effects on the tissue due to the active daily use of the system and the electrodes' proximity to the retina. The patients were able to integrate the system into their daily lives and perform activities that they could not do before. Studies on retinal prostheses for the rehabilitation of hereditary retinal diseases are ongoing, so both social and clinical observations and experiences related to the implant are valuable.
本研究介绍了 Argus II 视网膜假体植入术在 3 例晚期色素性视网膜炎患者中光感和投影眼的长期临床结果。术后随访期间，未观察到结膜侵蚀、低眼压或植入物移位。电阈值在黄斑区域较低，在接近钉固定区域和周边较高。光学相干断层扫描显示两例患者在视网膜-植入物界面处有纤维化和视网膜劈裂形成。这归因于系统的主动日常使用和电极靠近视网膜对组织产生的机械和电效应。患者能够将系统融入日常生活，并进行以前无法完成的活动。遗传性视网膜疾病的视网膜假体康复研究正在进行中，因此与植入物相关的社会和临床观察和经验都是有价值的。
