来自加纳的新种利什曼原虫（蒙迪尼亚）钱氏利什曼原虫（动质体目：锥虫科）及来自纳米比亚的新种利什曼原虫（蒙迪尼亚）普罗卡维恩斯利什曼原虫的描述、生物学特性及医学意义
DESCRIPTION, BIOLOGY, AND MEDICAL SIGNIFICANCE OF LEISHMANIA (MUNDINIA) CHANCEI N. SP. (KINETOPLASTEA: TRYPANOSOMATIDAE) FROM GHANA AND LEISHMANIA (MUNDINIA) PROCAVIENSIS N. SP. (KINETOPLASTEA: TRYPANOSOMATIDAE) FROM NAMIBIA.
作者信息
Kwakye-Nuako Godwin, Mosore Mba-Tihssommah, Boakye Daniel, Bates Paul A
机构信息
Department of Biomedical Sciences, University of Cape Coast, Cape Coast, Ghana.
U.S. Naval Medical Research Unit No. 3, Ghana Detachment, Accra, Ghana.
出版信息
J Parasitol. 2023 Jan 1;109(1):43-50. doi: 10.1645/22-53.
Genetic and phylogenetic analysis was performed on 2 isolates of Leishmania using DNA sequence data from the RNA polymerase II large subunit gene and the ribosomal protein L23a intergenic sequence. This showed the isolates to represent 2 new species within the subgenus Leishmania (Mundinia). The addition of Leishmania (Mundinia) chancei and Leishmania (Mundinia) procaviensis creates a total of 6 named species to date within this recently described subgenus of parasitic protozoa, containing both human pathogens and nonpathogens. Their widespread geographical distribution, basal phylogenetic position within the genus Leishmania, and probable non-sand fly vectors make these L. (Mundinia) species of significant medical and biological interest.
利用来自RNA聚合酶II大亚基基因和核糖体蛋白L23a基因间序列的DNA序列数据，对2株利什曼原虫进行了遗传和系统发育分析。结果表明，这些分离株代表了利什曼原虫（蒙迪尼亚亚属）中的2个新物种。利什曼原虫（蒙迪尼亚）钱氏种和利什曼原虫（蒙迪尼亚）豚鼠种的加入，使得在这个最近描述的寄生原生动物亚属中，迄今为止共有6个已命名的物种，其中包括人类病原体和非病原体。它们广泛的地理分布、在利什曼原虫属中的基础系统发育位置以及可能的非沙蝇传播媒介，使得这些利什曼原虫（蒙迪尼亚）物种具有重大的医学和生物学意义。
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