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Elemene sensitizes pancreatic cancer cells to bortezomib by enhancing proteasome inhibition via molecular patch mechanism.

作者信息

Hou Shurong, Li Zhenzhen, Chen Xiaoling, Wang Wenxin, Duan Ting, Scampavia Louis, Yuan Yaxia, Spicer Timothy P, Chen Xiabin, Xie Tian

机构信息

School of Pharmacy, Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines, Engineering Laboratory of Development and Application of Traditional Chinese Medicines, Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang, 311121, China.

Department of Pharmacology, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210023, China.

出版信息

Signal Transduct Target Ther. 2023 Feb 27;8(1):87. doi: 10.1038/s41392-023-01373-z.

DOI:10.1038/s41392-023-01373-z
PMID:36849489
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9971206/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/312f/9971206/316611567bed/41392_2023_1373_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/312f/9971206/316611567bed/41392_2023_1373_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/312f/9971206/316611567bed/41392_2023_1373_Fig1_HTML.jpg

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本文引用的文献

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BMC Complement Altern Med. 2019 Jun 18;19(1):133. doi: 10.1186/s12906-019-2544-2.
2
Elemene injection as adjunctive treatment to platinum-based chemotherapy in patients with stage III/IV non-small cell lung cancer: A meta-analysis following the PRISMA guidelines.榄香烯注射液联合含铂化疗方案治疗Ⅲ/Ⅳ期非小细胞肺癌的Meta 分析：遵循 PRISMA 指南。
Phytomedicine. 2019 Jun;59:152787. doi: 10.1016/j.phymed.2018.12.010. Epub 2018 Dec 10.
3
A Practical Review of Proteasome Pharmacology.
Bidirectional effects of morphine on pancreatic cancer progression via the p38/JNK pathway.
吗啡通过 p38/JNK 通路对胰腺癌进展的双向作用。
Sci Rep. 2024 Oct 16;14(1):24233. doi: 10.1038/s41598-024-75089-7.
4
Development of modern Chinese medicine guided by molecular compatibility theory.以分子配伍理论为指导的现代中医药发展。
J Adv Res. 2024 Aug 5. doi: 10.1016/j.jare.2024.08.005.
5
Ubiquitin-proteasome system as a target for anticancer treatment-an update.泛素-蛋白酶体系统作为抗癌治疗的靶点——更新。
Arch Pharm Res. 2023 Jul;46(7):573-597. doi: 10.1007/s12272-023-01455-0. Epub 2023 Aug 5.
6
Therapeutic Approaches in Pancreatic Cancer: Recent Updates.胰腺癌的治疗方法：最新进展
Biomedicines. 2023 Jun 1;11(6):1611. doi: 10.3390/biomedicines11061611.
蛋白酶体药理学实用综述。
Pharmacol Rev. 2019 Apr;71(2):170-197. doi: 10.1124/pr.117.015370.
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Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes.胰腺癌：临床诊断、流行病学、治疗和结局的综述。
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