Rial R V, Tur J A, Palmer A M, Tur J
Dept. of Biology and Health Sciences, Universitat de les Illes Balears, Ciutat de Mallorca, Spain.
Physiol Behav. 1987;41(2):119-23. doi: 10.1016/0031-9384(87)90140-5.
Hypothyroidal rats produced by low iodine diet or propylthiouracyl (PTU) were less active in the open field and received fewer food reinforcements than controls in a lever press situation at both 22 degrees C and 1 degree C. The hypothyroid rats also pressed less when heat was the reinforcer. On the other hand, hyperthyroidal rats produced by thyroid powder ingestion showed reduced emotionality in the open field. Acute exposure to cold failed to increase their alimentary or heat reinforced behavior. The results suggest that hypothyroidism produces a general inattention to the environment. This is found whether the environmental stimulus is an opportunity to explore, access to food or the availability of external heat.
通过低碘饮食或丙硫氧嘧啶（PTU）产生的甲状腺功能减退大鼠，在22摄氏度和1摄氏度的杠杆按压实验中，在旷场中活动较少，且获得的食物强化物比对照组少。当热量作为强化物时，甲状腺功能减退大鼠的按压次数也较少。另一方面，通过摄入甲状腺粉产生的甲状腺功能亢进大鼠在旷场中表现出情绪反应降低。急性暴露于寒冷环境未能增加它们的进食或热量强化行为。结果表明，甲状腺功能减退会导致对环境普遍缺乏关注。无论环境刺激是探索的机会、获取食物还是外部热量的可得性，均是如此。
