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新型冠状病毒肺炎相关肝损伤

COVID-19-Associated Liver Injury.

作者信息

Gildea Daniel T, Woo Stephanie M, O'Connor Corinne E, Rangnekar Amol S

机构信息

Department of Internal Medicine, MedStar Georgetown University Hospital, Washington, DC, USA.

Department of Gastroenterology, MedStar Georgetown University Hospital, Washington, DC, USA.

出版信息

Hepat Med. 2023 Feb 21;15:1-9. doi: 10.2147/HMER.S384108. eCollection 2023.

Abstract

This review analyzes data regarding liver injury associated with COVID-19 infection. We discuss reported effects on the liver from both COVID-19 and COVID-19 treatment as well as pathophysiology, review the potential role of drug-induced liver injury as an etiology of COVID-19-associated liver injury, and touch on other reports of significant outcomes including COVID-19 cholangiopathy and autoimmune hepatitis. Finally, we review the implications of COVID-19 infection in liver transplant recipients.

摘要

本综述分析了与新型冠状病毒肺炎(COVID-19)感染相关的肝损伤数据。我们讨论了COVID-19及其治疗对肝脏的已知影响以及病理生理学,回顾了药物性肝损伤作为COVID-19相关肝损伤病因的潜在作用,并提及了包括COVID-19胆管病和自身免疫性肝炎在内的其他重大结局报告。最后,我们回顾了COVID-19感染对肝移植受者的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2350/9960793/8e643724eeb1/HMER-15-1-g0001.jpg

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