Department of Clinical Oncology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
ENT and Head and Neck Research Center and Department, The Five Senses Health Institute, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Asian Pac J Cancer Prev. 2023 Feb 1;24(2):353-355. doi: 10.31557/APJCP.2023.24.2.353.
Metastasis is the most common event that determines survival in patients with breast cancer. The benefits of appropriate sleep in enhancing cancer patients' prognosis have been demonstrated. Likewise, emerging evidence has noted the positive impacts of regular circadian rhythm on cancer survival. Proper sleep and regular circadian rhythm can help to improve the cancer prognosis by enhancing the immune system. Besides, circadian rhythm disruption can assist cancer progression by promoting systemic inflammation. However, a recent study by Diamantopoulou et al. titled "The Metastatic Spread of Breast Cancer Accelerates during Sleep" demonstrated that sleep can aggravate breast cancer metastasis. This article outlines how the study design can affect this controversy.
转移是决定乳腺癌患者生存的最常见事件。适当的睡眠对提高癌症患者预后的益处已得到证实。同样，新出现的证据也注意到了规律的昼夜节律对癌症生存的积极影响。适当的睡眠和规律的昼夜节律可以通过增强免疫系统来帮助改善癌症预后。此外，昼夜节律紊乱可通过促进全身炎症促进癌症进展。然而，Diamantopoulou 等人最近题为“睡眠时乳腺癌转移加速”的研究表明，睡眠会加重乳腺癌转移。本文概述了研究设计如何影响这一争议。
