Soulen R L, Fishman E K, Pyeritz R E, Zerhouni E A, Pessar M L
Department of Radiology, Johns Hopkins Medical Institutions, Baltimore, MD 21205.
Radiology. 1987 Dec;165(3):697-701. doi: 10.1148/radiology.165.3.3685348.
Twenty-five patients with Marfan syndrome underwent computed tomography (CT) and magnetic resonance (MR) imaging. MR images were interpreted in blinded fashion and then the results were compared with findings from CT scans. MR imaging was found to be equivalent to CT in the depiction of aortic, dural, and hip abnormalities in patients who had not undergone surgery. MR imaging was superior to CT in evaluation of postoperative patients because the artifact produced by Bjork-Shiley or St. Jude valves precludes adequate evaluation of the aortic root on CT scans, while producing only a small inferior field distortion, a "pseudo-ventricular septal defect," on MR images. The absence of radiation exposure is another significant advantage for the relatively young Marfan syndrome population, who require serial studies. MR imaging is the modality of choice for evaluation and follow-up of patients with Marfan syndrome and offers an appropriate means of screening their kindred.
25例马凡综合征患者接受了计算机断层扫描（CT）和磁共振（MR）成像检查。MR图像由不知情的人员解读，然后将结果与CT扫描结果进行比较。结果发现，在未接受手术的患者中，MR成像在显示主动脉、硬脑膜和髋关节异常方面与CT相当。在评估术后患者时，MR成像优于CT，因为Bjork-Shiley或圣犹达瓣膜产生的伪影会妨碍在CT扫描上对主动脉根部进行充分评估，而在MR图像上仅产生较小的下视野畸变，即“假性室间隔缺损”。对于需要进行系列检查的相对年轻的马凡综合征患者群体而言，无辐射暴露是另一项显著优势。MR成像是评估马凡综合征患者并对其进行随访的首选方式，也是筛查其亲属的合适手段。
