Yang Yuyao, Hao Jingyu, Wu Shuicai
Department of Biomedical Engineering, Beijing University of Technology, Beijing 100124, P. R. China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2023 Feb 25;40(1):51-59. doi: 10.7507/1001-5515.202210071.
Fetal electrocardiogram (ECG) signals provide important clinical information for early diagnosis and intervention of fetal abnormalities. In this paper, we propose a new method for fetal ECG signal extraction and analysis. Firstly, an improved fast independent component analysis method and singular value decomposition algorithm are combined to extract high-quality fetal ECG signals and solve the waveform missing problem. Secondly, a novel convolutional neural network model is applied to identify the QRS complex waves of fetal ECG signals and effectively solve the waveform overlap problem. Finally, high quality extraction of fetal ECG signals and intelligent recognition of fetal QRS complex waves are achieved. The method proposed in this paper was validated with the data from the PhysioNet computing in cardiology challenge 2013 database of the Complex Physiological Signals Research Resource Network. The results show that the average sensitivity and positive prediction values of the extraction algorithm are 98.21% and 99.52%, respectively, and the average sensitivity and positive prediction values of the QRS complex waves recognition algorithm are 94.14% and 95.80%, respectively, which are better than those of other research results. In conclusion, the algorithm and model proposed in this paper have some practical significance and may provide a theoretical basis for clinical medical decision making in the future.
胎儿心电图(ECG)信号为胎儿异常的早期诊断和干预提供了重要的临床信息。在本文中,我们提出了一种新的胎儿心电图信号提取与分析方法。首先,将改进的快速独立成分分析方法与奇异值分解算法相结合,以提取高质量的胎儿心电图信号并解决波形缺失问题。其次,应用一种新颖的卷积神经网络模型来识别胎儿心电图信号的QRS复合波,并有效解决波形重叠问题。最后,实现了胎儿心电图信号的高质量提取和胎儿QRS复合波的智能识别。本文提出的方法通过来自复杂生理信号研究资源网络的2013年心脏病学挑战PhysioNet计算数据库的数据进行了验证。结果表明,提取算法的平均灵敏度和阳性预测值分别为98.21%和99.52%,QRS复合波识别算法的平均灵敏度和阳性预测值分别为94.14%和95.80%,均优于其他研究结果。总之,本文提出的算法和模型具有一定的实际意义,可能为未来临床医疗决策提供理论依据。