Kassem Sameer, Samuels Noah, Ben-Arye Eran
Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Department of Internal Medicine, Carmel Medical Center, Clalit Health Services, Michal 7, Haifa, Israel.
Curr Psychiatry Rep. 2025 Jul 14. doi: 10.1007/s11920-025-01623-7.
We review the literature on the interconnections between diabetes and mental health disorders, such as depression and anxiety, highlighting recent findings and potential integrative medicine (IM) interventions for improving patient care in individuals with both comorbidities.
Underscore the bidirectional relationship between diabetes and depression, with each condition exacerbating the other with associated poorer clinical outcomes. Pathophysiological mechanisms like hypothalamic-pituitary-adrenal (HPA) axis dysregulation and chronic inflammation contribute significantly. IM approaches, including mind-body therapies, dietary modifications, and herbal medicine, show promise in enhancing both glycemic control and mental health well-being. IM offers a holistic, patient-centered approach potentially improving care for individuals with diabetes and mental health disorders. While evidence supports the efficacy of various integrative therapies, further rigorous research is needed to standardize these interventions and ensure their effective integration into conventional medical practice.
我们回顾了关于糖尿病与精神健康障碍(如抑郁症和焦虑症)之间相互联系的文献,重点介绍了近期的研究发现以及可能用于改善合并这两种疾病患者护理的整合医学(IM)干预措施。
强调了糖尿病与抑郁症之间的双向关系,每种疾病都会使另一种疾病恶化,从而导致更差的临床结果。下丘脑 - 垂体 - 肾上腺(HPA)轴失调和慢性炎症等病理生理机制起了重要作用。整合医学方法,包括身心疗法、饮食调整和草药,在改善血糖控制和心理健康方面显示出前景。整合医学提供了一种整体的、以患者为中心的方法,有可能改善对糖尿病和精神健康障碍患者的护理。虽然有证据支持各种整合疗法的有效性,但需要进一步进行严格的研究,以规范这些干预措施,并确保它们有效地融入传统医疗实践。