Dijkman Henry B P M, Slaats Inca, Hughes Samantha
HAN University of Applied Sciences, Nijmegen, the Netherlands.
Amsterdam Institute for Life and Environment, Environmental Health and Toxicology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
MicroPubl Biol. 2023 Feb 8;2023. doi: 10.17912/micropub.biology.000732. eCollection 2023.
Women are raising concerns about breast implant illness (BII), a collective term for a range of symptoms attributed to gel bleed. To study this, was exposed to increasing duration of gel bleed from silicone breast implants (SBI) and the impact on health parameters observed. SBI exposure results in a slight reduction in total brood size with the progeny having impaired mobility. Nematodes displayed stress characteristics and silicones were detected inside the animals, suggesting silicone uptake after exposure to SBI. Our data highlights the need for more investigations into the mechanisms and pathways impacted by SBI.
女性对乳房植入物疾病（BII）表示担忧，这是一个用于描述一系列归因于凝胶渗漏症状的统称。为了研究这一问题，将其暴露于来自硅胶乳房植入物（SBI）的凝胶渗漏时间不断增加的环境中，并观察对健康参数的影响。暴露于SBI会导致总产卵量略有减少，后代的活动能力受损。线虫表现出应激特征，并且在动物体内检测到了硅酮，这表明暴露于SBI后会摄取硅酮。我们的数据凸显了需要对受SBI影响的机制和途径进行更多研究。
