Yamauchi T
Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock.
Semin Respir Infect. 1987 Sep;2(3):184-7.
The development of antiviral drugs is changing the specific treatment of viral pneumonias. Today the clinician is able to diagnose the cause of some viral pneumonias early enough that specific therapy can be initiated. Although symptomatic treatment remains an important component of therapy, specific antiviral drugs are playing a more important role. No single antiviral agent has been demonstrated effective against all respiratory viruses. Some antiviral agents appear to be more effective used as prophylaxis or to prevent dissemination of disease; while others lessen symptoms, duration of illness, and viral shedding. Spectrum of activity, dosage, adverse reaction, and cost of the approved antiviral drugs useful in viral pneumonia is presented.
抗病毒药物的发展正在改变病毒性肺炎的具体治疗方式。如今,临床医生能够足够早地诊断出某些病毒性肺炎的病因,从而可以启动特异性治疗。尽管对症治疗仍然是治疗的重要组成部分,但特异性抗病毒药物正发挥着更重要的作用。尚无单一抗病毒药物被证明对所有呼吸道病毒均有效。一些抗病毒药物似乎作为预防用药或预防疾病传播时更有效;而其他药物则可减轻症状、缩短病程并减少病毒排出。本文介绍了可用于病毒性肺炎的已批准抗病毒药物的活性谱、剂量、不良反应及费用。