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评估希腊和葡萄牙肾癌相关过早死亡和生产力损失的影响。

Assessing the impact of kidney cancer-related premature mortality and productivity loss in Greece and Portugal.

作者信息

Bencina Goran, Chami Nour, Hughes Robert, Weston Georgie, Baxter Carl, Salomonsson Stina

机构信息

Center for Observational and Real-World Evidence, MSD, Spain, Madrid.

Adelphi Values Ltd, Bollington, UK.

出版信息

Expert Rev Pharmacoecon Outcomes Res. 2023 Apr;23(4):391-398. doi: 10.1080/14737167.2023.2180356. Epub 2023 Mar 1.

Abstract

OBJECTIVE

In 2018, 371,750 people were diagnosed with kidney cancer globally, constituting 2.2% of all cancer diagnoses. Since 2010, the number of kidney cancer deaths in Europe have decreased in people under 65. However, this is not the case in Greece and Portugal. This study estimated the mortality and lost productivity due to premature mortality from kidney cancer in Greece and Portugal.

METHODS

Years of life lost (YLL) and present value of future lost productivity (PVFLP) due to kidney cancer mortality (ICD-10 code: C64 - Malignant neoplasm of kidney, except renal pelvis) were calculated using the human capital approach. Age-specific mortality, mean earnings, and labor force participation rates were used in these calculations.

RESULTS

In 2019, there were 564 and 454 kidney cancer deaths in Greece and Portugal, respectively, resulting in 5,871 (3,636 in males and 2,234 in females) and 5,397 (3,100 in males and 2,297 in females) YLL, respectively. YPLL and annual PVFLP were estimated to be 1,326 and €14.8 M in Greece and 1,278 and €11.8 M in Portugal, respectively.

CONCLUSION

YLL and PVFLP due to kidney cancer mortality are substantial in Greece and Portugal. These results provide new evidence to assist decision-makers in allocating resources to reduce cancer burden.

摘要

目的

2018年,全球有371,750人被诊断出患有肾癌,占所有癌症诊断病例的2.2%。自2010年以来,欧洲65岁以下人群的肾癌死亡人数有所下降。然而,希腊和葡萄牙的情况并非如此。本研究估计了希腊和葡萄牙因肾癌过早死亡导致的死亡率和生产力损失。

方法

采用人力资本法计算因肾癌死亡率(国际疾病分类第十版代码:C64——肾恶性肿瘤,肾盂除外)导致的寿命损失年数(YLL)和未来生产力损失的现值(PVFLP)。这些计算中使用了特定年龄的死亡率、平均收入和劳动力参与率。

结果

2019年,希腊和葡萄牙分别有564例和454例肾癌死亡,分别导致5,871例(男性3,636例,女性2,234例)和5,397例(男性3,100例,女性2,297例)寿命损失年数。希腊的YPLL和年度PVFLP估计分别为1,326例和1480万欧元,葡萄牙分别为1,278例和1180万欧元。

结论

希腊和葡萄牙因肾癌死亡导致的YLL和PVFLP相当可观。这些结果为协助决策者分配资源以减轻癌症负担提供了新的证据。

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