Department of Animal Medicine, Production and Health, University of Padova, Viale dell'Università 16, 35020, Legnaro, PD, Italy.
Acta Vet Scand. 2023 Mar 1;65(1):10. doi: 10.1186/s13028-023-00673-2.
Endotracheal intubation in rabbits is challenging and supraglottic airway devices, such as laryngeal masks (LMA), represent an alternative as they are easy to insert, and do not stimulate the larynx requiring therefore a lighter plane of anaesthesia for their insertion and positioning than the endotracheal tubes. We investigated whether, compared to an endotracheal tube, the LMA can reduce the negative effects of general anaesthetics on some cardiovascular and respiratory parameters routinely monitored in rabbits anaesthetized for elective gonadectomy. The records of 21 adult mixed breed pet rabbits were collected retrospectively. Rabbits were divided in two groups based on the type of airway device used. A laryngeal mask secured the airway in group LMA (n = 11), and in group ETT (n = 10) an endotracheal tube was used. The amount of propofol used before successful insertion of the airway device was recorded. A pitot-based spirometer was connected and ventilatory variables were measured immediately after insertion. Pulse rate, non-invasive arterial blood pressure, haemoglobin oxygen saturation, respiratory rate, end-tidal carbon dioxide and volatile anaesthetic consumption were also monitored during the surgical procedure; extubation time was noted as well.
The use of LMA required significantly less propofol (0.8 to 4 mg/kg) for insertion than the ETT (1.2 to 5.6 mg/kg), and the difference was statistically significant (P < 0.01). No differences were observed in ventilatory variables measured immediately after airway positioning. Intraoperatively, there were no differences between groups for respiratory and cardiovascular variables, and amount of isoflurane administered. In all rabbits mean and diastolic blood pressure progressively decreased during surgery. Mean extubation time was shorter in group LMA (6 ± 2 min) than group ETT (8 ± 3 min, P < 0.01).
The airway device did not clinically affect the cardiovascular and respiratory variables during anaesthesia. Intraoperative hypoventilation was observed in most rabbits regardless of the device being used; therefore ventilatory support may be required. Rabbits with the laryngeal masks were extubated earlier.
在兔子中进行气管插管具有挑战性,而声门上气道装置(如喉罩)则是一种替代方法,因为它们易于插入,并且在插入和定位时不会刺激喉咙,因此需要比气管内导管更轻的麻醉平面。我们研究了与气管内导管相比,喉罩是否可以减轻在接受择期去势术麻醉的兔子中常规监测的一些心血管和呼吸参数的全身麻醉的负面影响。回顾性收集了 21 只成年混合品种宠物兔的记录。根据使用的气道装置类型将兔子分为两组。在 LMA 组(n=11)中使用喉罩来确保气道通畅,而在 ETT 组(n=10)中使用气管内导管。记录成功插入气道装置前使用的异丙酚量。连接基于皮托管的测振仪,并在插入后立即测量通气变量。在手术过程中还监测了脉搏率、无创动脉血压、血红蛋白氧饱和度、呼吸频率、呼气末二氧化碳和挥发性麻醉剂的消耗;还记录了拔管时间。
LMA 的使用量为 0.8 至 4mg/kg,明显少于 ETT(1.2 至 5.6mg/kg),差异具有统计学意义(P<0.01)。气道定位后立即测量的通气变量无差异。术中,两组的呼吸和心血管变量以及异氟烷用量无差异。在所有兔子中,平均和舒张压在手术过程中逐渐下降。LMA 组(6±2 分钟)的平均拔管时间短于 ETT 组(8±3 分钟,P<0.01)。
气道装置在麻醉期间并未对心血管和呼吸变量产生临床影响。无论使用何种装置,大多数兔子都出现术中通气不足;因此可能需要通气支持。使用喉罩的兔子拔管更早。