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昆虫附肢再生的生理和分子机制。

Physiological and molecular mechanisms of insect appendage regeneration.

作者信息

Zhong Jiru, Jing Andi, Zheng Shaojuan, Li Sheng, Zhang Xiaoshuai, Ren Chonghua

机构信息

Guangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Guangzhou Key Laboratory of Insect Development Regulation and Application Research, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou, 510631, China.

Guangmeiyuan R&D Center, Guangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, South China Normal University, Meizhou, 514779, China.

出版信息

Cell Regen. 2023 Mar 2;12(1):9. doi: 10.1186/s13619-022-00156-1.

DOI:10.1186/s13619-022-00156-1
PMID:36859631
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9978051/
Abstract

Regeneration, as a fascinating scientific field, refers to the ability of animals replacing lost tissue or body parts. Many metazoan organisms have been reported with the regeneration phenomena, but showing evolutionarily variable abilities. As the most diverse metazoan taxon, hundreds of insects show strong appendage regeneration ability. The regeneration process and ability are dependent on many factors, including macroscopic physiological conditions and microscopic molecular mechanisms. This article reviews research progress on the physiological conditions and internal underlying mechanisms controlling appendage regeneration in insects.

摘要

再生作为一个引人入胜的科学领域,是指动物替换失去的组织或身体部位的能力。许多后生动物已被报道具有再生现象,但显示出进化上可变的能力。作为最多样化的后生动物类群,数百种昆虫表现出强大的附肢再生能力。再生过程和能力取决于许多因素,包括宏观生理条件和微观分子机制。本文综述了昆虫附肢再生生理条件和内在控制机制的研究进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/930f/9978051/d3404384c019/13619_2022_156_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/930f/9978051/d3404384c019/13619_2022_156_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/930f/9978051/d3404384c019/13619_2022_156_Fig1_HTML.jpg

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本文引用的文献

1
Hedgehog signaling.刺猬信号通路。
Curr Top Dev Biol. 2022;149:1-58. doi: 10.1016/bs.ctdb.2022.04.003. Epub 2022 May 6.
2
Toll signalling promotes blastema cell proliferation during cricket leg regeneration via insect macrophages.Toll 信号通路通过昆虫巨噬细胞促进蟋蟀腿部再生中的芽基细胞增殖。
Development. 2022 Apr 15;149(8). doi: 10.1242/dev.199916. Epub 2021 Nov 9.
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Biological insights into the rapid tissue regeneration of freshwater crayfish and crustaceans.淡水螯虾和甲壳类动物快速组织再生的生物学见解。
小型水栖步行昆虫的肢体缺失与特殊腿部动力学
bioRxiv. 2024 Apr 2:2024.04.02.587762. doi: 10.1101/2024.04.02.587762.
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ERK-activated CK-2 triggers blastema formation during appendage regeneration.ERK 激活的 CK-2 触发附肢再生过程中的芽基形成。
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Nutrition and PI3K/Akt signaling are required for p38-dependent regeneration.营养和 PI3K/Akt 信号通路对于依赖于 p38 的再生是必需的。
Development. 2021 Apr 15;148(8). doi: 10.1242/dev.197087. Epub 2021 Apr 23.
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The engine initiating tissue regeneration: does a common mechanism exist during evolution?启动组织再生的引擎:进化过程中是否存在共同机制?
Cell Regen. 2021 Apr 5;10(1):12. doi: 10.1186/s13619-020-00073-1.
6
The Ras/MAPK pathway is required for regenerative growth of wing discs in the black cutworm Agrotis ypsilon.Ras/MAPK 通路对于黑光灯蛾 Agrotis ypsilon 的翅膀盘再生性生长是必需的。
Insect Biochem Mol Biol. 2021 Apr;131:103552. doi: 10.1016/j.ibmb.2021.103552. Epub 2021 Feb 9.
7
Control of osteoblast regeneration by a train of Erk activity waves.通过一连串 Erk 活性波控制成骨细胞的再生。
Nature. 2021 Feb;590(7844):129-133. doi: 10.1038/s41586-020-03085-8. Epub 2021 Jan 6.
8
Hedgehog signaling regulates regenerative patterning and growth in Harmonia axyridis leg.刺猬信号通路调控东亚飞蝗附肢的再生模式和生长。
Cell Mol Life Sci. 2021 Mar;78(5):2185-2197. doi: 10.1007/s00018-020-03631-7. Epub 2020 Sep 9.
9
Model systems for regeneration: .再生模型系统: 。
Development. 2020 Apr 6;147(7):dev173781. doi: 10.1242/dev.173781.
10
Evolution and Regulation of Limb Regeneration in Arthropods.节肢动物肢体再生的进化与调控
Results Probl Cell Differ. 2019;68:419-454. doi: 10.1007/978-3-030-23459-1_17.