Department of Anorectal Surgery, Shaoxing People's Hospital, Zhejiang, China.
Int Wound J. 2023 Aug;20(6):2151-2158. doi: 10.1111/iwj.14091. Epub 2023 Mar 1.
We conducted a meta-analysis to assess the effect of different body mass index on surgical wound infection after colorectal surgery. A systematic literature search up to November 2022 was performed and 2349 related studies were evaluated. The chosen studies comprised 15 595 colorectal surgery subjects participated in the selected studies' baseline trials; 4390 of them were obese according to the selected body mass index cut-off used to measure obesity in the selected studies, while 11 205 were nonobese. Odds ratio (OR) with 95% confidence intervals (CIs) were calculated to assess the effect of different body mass index on wound infection after colorectal surgery by the dichotomous methods with a random or fixed effect model. The body mass index ≥30 kg/m resulted in significantly higher surgical wound infection after colorectal surgery (OR, 1.76; 95% CI, 1.46-2.11, P < .001) compared with the body mass index <30 kg/m . The body mass index ≥25 kg/m resulted in significantly higher surgical wound infection after colorectal surgery (OR, 1.64; 95% CI, 1.40-1.92, P < .001) compared with the body mass index <25 kg/m . The subjects with higher body mass index had a significantly higher surgical wound infection after colorectal surgery compared with the subjects with normal body mass index.
我们进行了一项荟萃分析，以评估不同体重指数对结直肠手术后手术部位感染的影响。系统检索截至 2022 年 11 月，评估了 2349 项相关研究。入选的研究包括 15595 例接受结直肠手术的受试者，他们均参加了入选研究的基线试验；根据入选研究中用于测量肥胖的体重指数切点，其中 4390 例为肥胖，11205 例为非肥胖。采用二项式方法，以随机或固定效应模型计算比值比（OR）及其 95%置信区间（CI），以评估不同体重指数对结直肠手术后手术部位感染的影响。与体重指数<30kg/m2相比，体重指数≥30kg/m2 导致结直肠手术后手术部位感染的风险显著增加（OR，1.76；95%CI，1.46-2.11，P<0.001）。与体重指数<25kg/m2相比，体重指数≥25kg/m2 导致结直肠手术后手术部位感染的风险显著增加（OR，1.64；95%CI，1.40-1.92，P<0.001）。与体重正常的受试者相比，体重指数较高的受试者结直肠手术后手术部位感染的风险显著增加。
