Jenkins J K, Best T R, Nicks S A, Murphy F Y, Bussell K L, Vesely D L
Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock.
South Med J. 1987 Nov;80(11):1444-9. doi: 10.1097/00007611-198711000-00028.
A man with severe hypercalcemia (22 mg/dl) secondary to ingestion of a calcium carbonate antacid (Tums) was admitted with obtundation and hyperreflexia, which disappeared with treatment. Laboratory values, which were consistent with milk-alkali syndrome, included low-normal serum chloride (96 mEq/L), normal phosphorus of 2.7 mg/dl (phosphorus is usually normal to increased in this syndrome), increased blood urea nitrogen (39 mg/dl), and increased serum creatinine (2.4 mg/dl). A normal C-terminal parathormone level helped distinguish this patient from patients with severe hypercalcemia due to primary hyperthyroidism. The ECG revealed a widened rather than a shortened QT interval, as well as a J wave, a broadened T wave, and a U wave with this marked hypercalcemia, all of which reverted to normal with correction of the hypercalcemia.
一名因摄入碳酸钙抗酸剂（达喜）继发严重高钙血症（22毫克/分升）的男性患者，因意识模糊和反射亢进入院，经治疗后症状消失。与乳碱综合征相符的实验室检查结果包括血清氯略低（96毫当量/升）、磷正常为2.7毫克/分升（该综合征中磷通常正常或升高）、血尿素氮升高（39毫克/分升）以及血清肌酐升高（2.4毫克/分升）。正常的C末端甲状旁腺激素水平有助于将该患者与原发性甲状旁腺功能亢进导致的严重高钙血症患者区分开来。心电图显示QT间期增宽而非缩短，以及出现J波、T波增宽和U波，这些均在高钙血症纠正后恢复正常。
