Waked Alain, Geara Abdallah, El-Imad Badiaa
Department of Medicine, Staten Island University Hospital, 27 Hickory Avenue, Staten Island, NY 10305, USA.
Cases J. 2009 Aug 6;2:6188. doi: 10.4076/1757-1626-2-6188.
We report a case of a patient presenting with a triad of hypercalcemia, metabolic alkalosis and renal failure secondary to calcium bicarbonate intake for osteoporosis prevention. It is the classical presentation of the "modern" milk alkali syndrome that presents several characteristics distinguishing it from the "old" syndrome described secondary to peptic ulcer disease treatment. Milk alkali syndrome affects middle-aged female patients taking over-the-counter calcium carbonate. Clinically, these patients present in an acute hypercalcemia crisis, responding rapidly to hydration. The phosphorus level is normal to low. Bisphosphonate should be used cautiously due to the risk of symptomatic hypocalcemia.
我们报告了一例患者，该患者因预防骨质疏松症摄入碳酸氢钙而出现高钙血症、代谢性碱中毒和肾衰竭三联征。这是“现代”乳碱综合征的典型表现，它具有一些特征，使其有别于继发于消化性溃疡疾病治疗的“旧”综合征。乳碱综合征影响服用非处方碳酸钙的中年女性患者。临床上，这些患者表现为急性高钙血症危象，对补液反应迅速。磷水平正常或偏低。由于存在出现症状性低钙血症的风险，应谨慎使用双膦酸盐。
