Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, Shanghai Key Laboratory of New Drug Design, and School of Pharmacy, East China University of Science and Technology, Shanghai 200237, P. R. China.
State Key Laboratory of Bioreactor Engineering, Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, Frontiers Science Center for Materiobiology and Dynamic Chemistry, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, P. R. China.
Org Lett. 2023 Mar 10;25(9):1386-1391. doi: 10.1021/acs.orglett.3c00096. Epub 2023 Mar 2.
A visible-light-induced photocatalytic C-Si formation strategy has been disclosed by uncovering the reactivity of Martin's spirosilane-derived pentacoordinate silylsilicates as silyl radical precursors. The hydrosilylation of a broad spectrum of alkenes and alkynes, as well as the C-H silylation of heteroarenes, has been demonstrated. Remarkably, Martin's spirosilane was stable and could be recovered via a simple workup process. Furthermore, the reaction proceeded well using water as the solvent or low-energy green LEDs as an alternative energy source.
本研究揭示了 Martin 螺硅烷衍生的五配位硅基硅酸盐作为硅自由基前体的反应活性，从而提出了一种可见光诱导的光催化 C-Si 形成策略。该策略展示了对广泛的烯烃和炔烃的硅氢化反应，以及杂芳烃的 C-H 硅化反应。值得注意的是，Martin 螺硅烷稳定且可通过简单的后处理过程回收。此外，该反应在水作为溶剂或低能量绿色 LED 作为替代能源的情况下也能很好地进行。
