Müller Manfred J, Heymsfield Steven B, Bosy-Westphal Anja
Institute of Human Nutrition and Food Science, Christian-Albrechts-Universität zu Kiel, Kiel, Germany.
Pennington Biomedical Research Center, LSU System, Baton Rouge, Louisiana, USA.
Obesity (Silver Spring). 2023 Apr;31(4):892-895. doi: 10.1002/oby.23703. Epub 2023 Mar 2.
Adaptive thermogenesis (AT) is the mass-independent decrease in energy expenditure (EE) in response to caloric restriction and weight loss. AT becomes manifest throughout all periods of weight loss and persists during subsequent weight maintenance. AT occurs in resting and nonresting energy expenditure as AT and AT , respectively. AT appears in different phases of weight loss, each with likely different mechanisms. By contrast, during weight maintenance after weight loss, AT exceeds AT . Some of the mechanisms of AT are known now and others are not. Future studies on AT will need an appropriate conceptual framework within which to design experiments and interpret results.
适应性产热（AT）是指机体在热量限制和体重减轻时，能量消耗（EE）出现与体重无关的减少。在体重减轻的各个阶段都会出现适应性产热，并在随后的体重维持期持续存在。适应性产热分别以静息适应性产热和非静息适应性产热的形式出现在静息和非静息能量消耗过程中。适应性产热出现在体重减轻的不同阶段，每个阶段可能具有不同的机制。相比之下，在体重减轻后的体重维持期，非静息适应性产热超过静息适应性产热。目前已知部分适应性产热的机制，部分机制尚不清楚。未来关于适应性产热的研究需要一个合适的概念框架来设计实验并解释结果。
