综合应用行为分析（ABA）干预自闭症谱系障碍儿童的治疗效果 - 一项荟萃分析。 - Suppr

Comprehensive ABA-based interventions in the treatment of children with autism spectrum disorder - a meta-analysis.

机构信息

Institute of Psychology, University of Münster, Fliednerstr. 21, 48149, Münster, Germany.

Institute of Psychology, Clinical Psychology and Psychotherapy, University of Bremen, Grazer Str. 6, 28359, Bremen, Germany.

出版信息

BMC Psychiatry. 2023 Mar 2;23(1):133. doi: 10.1186/s12888-022-04412-1.

BACKGROUND

Many studies display promising results for interventions that are based on Applied Behavior Analysis (ABA) in the treatment of autism spectrum disorder (ASD).

METHODS

This meta-analysis assessed the effects of such treatments on developmental outcomes in children with ASD and on parental stress based on 11 studies with 632 participants.

RESULTS

Compared to treatment as usual, minimal or no treatment, comprehensive ABA-based interventions showed medium effects for intellectual functioning (standardized mean difference SMD = 0.51, 95% CI [0.09; 0.92]) and adaptive behavior (SMD = 0.37, 95% CI [0.03; 0.70]). Language abilities, symptom severity or parental stress did not improve beyond the improvement in control groups. Moderator analyses indicate that language abilities at intake could influence the effect sizes and the influence of treatment intensity might decrease with older age.

CONCLUSIONS

Practical implications and limitations are discussed.

背景

许多研究显示，基于应用行为分析（ABA）的干预措施在自闭症谱系障碍（ASD）的治疗中具有前景。

方法

本荟萃分析评估了这些治疗方法对 ASD 儿童发育结果和父母压力的影响，共纳入了 11 项研究，涉及 632 名参与者。

结果

与常规治疗、最小或无治疗相比，基于全面 ABA 的干预措施对智力功能（标准化均数差 SMD=0.51，95%置信区间 [0.09; 0.92]）和适应行为（SMD=0.37，95%置信区间 [0.03; 0.70]）具有中等效应。语言能力、症状严重程度或父母压力的改善并未超过对照组的改善。调节分析表明，入学时的语言能力可能会影响效应大小，而治疗强度的影响可能会随着年龄的增长而降低。