Shinde Mitali R, Winnier J Jasmin
Department of Pedodontics and Preventive Dentistry, School of Dentistry, D Y Patil University (DYPU) (Deemed to be University), Navi Mumbai, Maharashtra, India.
Int J Clin Pediatr Dent. 2022 Sep-Oct;15(5):554-557. doi: 10.5005/jp-journals-10005-2429.
The etiology of molar incisor hypomineralization (MIH) has been extensively explored. Recently, the effect of drugs used in aerosol therapy in childhood has been implicated as a possible factor in the development of MIH.
A case-control study was conducted in children aged 6-13 years to determine the association between aerosol therapy and other factors in the development of MIH.
A total of 200 children were examined for the presence of MIH according to the European Academy of Paediatric Dentistry (EAPD) criteria (2003). Their mothers or primary caregivers were interviewed regarding the preterm history and perinatal, and postnatal history of the child up to 3 years of life.
The collected data were subjected to statistical analysis using descriptive and inferential analyses. The -value ≤ 0.05 was considered statistically significant.
Statistically significant association was observed between the development of MIH and exposure to aerosol therapy in childhood and the use of antibiotics before 1 year of life.
Exposure to aerosol therapy and antibiotics before 1 year of age are risk factors in MIH. Children who had aerosol therapy and antibiotics are 2.01 times and 1.61 times more prone to MIH.
Shinde MR, Winnier JJ. Correlation between Aerosol Therapy and Other Associated Factors in Early Childhood with Molar Incisor Hypomineralization. Int J Clin Pediatr Dent 2022;15(5):554-557.
磨牙切牙矿化不全(MIH)的病因已得到广泛研究。最近,儿童期雾化治疗中使用的药物被认为是MIH发生的一个可能因素。
对6至13岁的儿童进行病例对照研究,以确定雾化治疗及其他因素与MIH发生之间的关联。
根据欧洲儿童牙科学会(EAPD)标准(2003年)对总共200名儿童进行MIH检查。就其早产史、围产期及出生后至3岁的病史对他们的母亲或主要照顾者进行访谈。
使用描述性和推断性分析对收集的数据进行统计分析。P值≤0.05被认为具有统计学意义。
观察到MIH的发生与儿童期接受雾化治疗以及1岁前使用抗生素之间存在统计学上的显著关联。
1岁前接受雾化治疗和使用抗生素是MIH的危险因素。接受雾化治疗和使用抗生素的儿童患MIH的可能性分别是其他儿童的2.01倍和1.61倍。
Shinde MR, Winnier JJ. 幼儿期雾化治疗及其他相关因素与磨牙切牙矿化不全的相关性。《国际临床儿科牙科学杂志》2022;15(5):554 - 557。