Tan Sean Y, M Leong Sean W, Hsu Chin-Ying S, Chandran Nisha S
Division of Dermatology, Department of Medicine, National University Hospital, 5 Lower Kent Ridge Road, Singapore.
National Skin Centre, 1 Mandalay Road, Singapore.
Indian J Dermatol. 2022 Sep-Oct;67(5):539-542. doi: 10.4103/ijd.ijd_375_22.
Atopic dermatitis is a common inflammatory skin condition with an underlying pathophysiology that may have impact beyond the skin. Previous studies showed a higher prevalence of dental cavities in patients with atopic dermatitis. Our study aimed to establish an association of other dental anomalies in patients with moderate-severe atopic dermatitis. We prospectively recruited 15 patients with moderate-severe atopic dermatitis for a formal dental examination by a paediatric dentist. Hypodontia and microdontia were more prevalent in patients with moderate-severe atopic dermatitis as compared to reference populations and were statistically significant. Dental caries, enamel hypoplasia and agenesis of 3 molars were also prevalent but did not reach statistical significance. Our study shows a novel finding of higher prevalence of dental anomalies in patients with moderate-severe atopic dermatitis which may warrant further investigation due to its clinical implications.
特应性皮炎是一种常见的炎症性皮肤病,其潜在的病理生理学影响可能超出皮肤范围。先前的研究表明,特应性皮炎患者龋齿的患病率较高。我们的研究旨在确定中重度特应性皮炎患者中其他牙齿异常之间的关联。我们前瞻性地招募了15名中重度特应性皮炎患者,由一名儿科牙医进行正式的牙科检查。与参考人群相比,中重度特应性皮炎患者的牙齿发育不全和过小牙更为普遍,且具有统计学意义。龋齿、釉质发育不全和3颗磨牙的先天性缺失也很普遍,但未达到统计学意义。我们的研究显示了一个新发现,即中重度特应性皮炎患者牙齿异常的患病率较高,鉴于其临床意义,可能需要进一步研究。