Abe Masanobu, Mitani Akihisa, Hoshi Kazuto, Yanagimoto Shintaro
Division for Health Service Promotion, University of Tokyo, Tokyo 113-0033, Japan.
Department of Oral & Maxillofacial Surgery, University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.
J Clin Med. 2024 Oct 12;13(20):6087. doi: 10.3390/jcm13206087.
Toothbrushing is important for maintaining oral health and preventing periodontal disease. However, the association between toothbrushing and systemic diseases remains unclear in adolescence. In this study, the association between dental self-care (frequency and duration of toothbrushing) and systemic diseases/disorders in adolescents was examined. We conducted a retrospective review of mandatory medical questionnaires administered during legally mandated freshman medical checkups between 2017 and 2019 at the University of Tokyo, Japan. Out of 9376 total responses, 9098 cases involving individuals under the age of 20 were included in the analysis. Respondents were classified into three groups based on their daily toothbrushing frequency: "1 time or less", "twice", and "3 times or more". For the duration of each toothbrushing session, they were classified into three groups: "1 min or less", "2-3 min", and "4 min or more". A statistical analysis was performed by Pearson's test and multinomial logistic regression analysis. Regarding frequency of daily toothbrushing: The test showed no significant relationship between frequency of toothbrushing and 17 systemic diseases/disorders. A multivariate analysis found that gingival bleeding and sex were independent factors. The risk of gingival bleeding decreased dramatically with increased frequency of toothbrushing (odds ratio (OR): 0.428; 95% confidence interval (CI), 0.366-0.501; < 0.001). Regarding the amount of time spent on toothbrushing: The test showed atopic dermatitis and arrhythmia were significantly associated with the duration of toothbrushing ( = 0.032 and = 0.016, respectively). In the multivariate analysis, atopic dermatitis, gingival bleeding, and sex were independent factors regarding the duration of toothbrushing; longer brushing time was associated with a lower risk of atopic dermatitis (OR: 0.731, 95% CI: 0.578-0.924, = 0.009) and a lower risk of gingival bleeding (OR: 0.643, 95% CI: 0.567-0.729, < 0.001). Dental self-care was most strongly associated with gingival bleeding, while the risk of atopic dermatitis was found to increase with shorter toothbrushing times. The results suggest that dental self-care during adolescence is important not only for oral health but also for general health.
刷牙对于维护口腔健康和预防牙周疾病至关重要。然而，在青少年中，刷牙与全身性疾病之间的关联仍不明确。在本研究中，我们调查了青少年牙齿自我护理（刷牙频率和时长）与全身性疾病/病症之间的关联。我们对2017年至2019年期间在日本东京大学依法进行的新生体检中所使用的强制性医疗问卷进行了回顾性分析。在总共9376份回复中，9098例涉及20岁以下个体的回复被纳入分析。根据受访者的每日刷牙频率，他们被分为三组：“1次及以下”、“2次”和“3次及以上”。对于每次刷牙的时长，他们被分为三组：“1分钟及以下”、“2 - 3分钟”和“4分钟及以上”。通过Pearson检验和多项逻辑回归分析进行统计分析。关于每日刷牙频率：检验表明刷牙频率与17种全身性疾病/病症之间无显著关系。多变量分析发现牙龈出血和性别是独立因素。随着刷牙频率增加，牙龈出血风险显著降低（优势比（OR）：0.428；95%置信区间（CI），0.366 - 0.501；P < 0.001）。关于刷牙时长：检验表明特应性皮炎和心律失常与刷牙时长显著相关（分别为P = 0.032和P = 0.016）。在多变量分析中，特应性皮炎、牙龈出血和性别是与刷牙时长相关的独立因素；刷牙时间越长，特应性皮炎风险越低（OR：0.731，95% CI：0.578 - 0.924，P = 0.009），牙龈出血风险也越低（OR：0.643，95% CI：0.567 - 0.729，P < 0.001）。牙齿自我护理与牙龈出血关联最为紧密，而特应性皮炎风险则随着刷牙时间缩短而增加。结果表明，青少年时期的牙齿自我护理不仅对口腔健康很重要，对整体健康也很重要。
