Bogatskaia L N, Pisaruk A V
Ukr Biokhim Zh (1978). 1987 Sep-Oct;59(5):81-3.
Reasons which have induced changes in the glycolysis rate, ATP and 2,3-diphosphoglycerate content in human erythrocytes with ageing are studied. A fall of the hexokinase activity is shown to be one of the reasons of a significant decrease in the glycolysis rate. The total ATPase activity in erythrocytes does not change with the age. At the same time the decay rate of 2,3-diphosphoglycerate increases, that, evidently, is one of the reasons of the 2,3-diphosphoglycerate content decrease in erythrocytes with ageing.
研究了随着衰老导致人类红细胞糖酵解速率、ATP和2,3 - 二磷酸甘油酸含量发生变化的原因。已表明己糖激酶活性下降是糖酵解速率显著降低的原因之一。红细胞中的总ATP酶活性不随年龄变化。与此同时，2,3 - 二磷酸甘油酸的分解速率增加，这显然是随着衰老红细胞中2,3 - 二磷酸甘油酸含量降低的原因之一。
