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[氢化可的松给药后大鼠肝脏核膜和染色质的中性脂质]

[Neutral lipids of nuclear membranes and chromatin in rat liver after hydrocortisone administration].

作者信息

Gevorkian E S, Iavroian Zh V, Panosian G A

出版信息

Ukr Biokhim Zh (1978). 1987 Sep-Oct;59(5):87-90.

PMID:3686700
Abstract

It is shown that over 80% of nuclear neutral lipids are found in the nuclear membrane preparations, whereas only 7%--in chromatin. The injection of hydrocortisone to animals significantly decreases the neutral lipids content in both fractions. These results and the data obtained previously by the authors indicate the possible participation of nuclear membrane and chromatin lipids in the process of hormonal regulation of the genetic activity.

摘要

结果显示,超过80%的核中性脂质存在于核膜制剂中,而染色质中仅占7%。给动物注射氢化可的松会显著降低这两个组分中的中性脂质含量。这些结果以及作者之前获得的数据表明,核膜和染色质脂质可能参与了遗传活性的激素调节过程。

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Ukr Biokhim Zh (1978). 1987 Sep-Oct;59(5):87-90.
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