Neutral lipids in nuclei and chromatin fraction of young and old Ehrlich ascites tumor cells.

Determination of lipid content of Ehrlich ascites tumor cell nuclei devoid of the nuclear envelope and chromatin isolated from them revealed considerable amounts of neutral lipids present in both preparations. The neutral lipid content always exceeded that of the phospholipid. An age dependent accumulation of neutral lipids could also be observed. The chromatin fraction always contained relatively higher amounts of neutral lipids than the respective nuclei with a predominance of cholesterol esters.