耶氏肺孢子菌和蜚蠊滴虫合并感染导致一名肺癌腺癌患者发生肺炎。

A co-infection of Pneumocystis jirovecii and Lophomonas blattarum causing pneumonia in a patient with adenocarcinoma of lung.

作者信息

Thakkar Pooja, Shah Sweta, Devadiga Ashavari, Singhania Sumeet

机构信息

Microbiology Department, Kokilaben Dhirubhai Ambani Hospital and Research Institute, Achyutrao Patwardhan Marg, Andheri West, Mumbai 400053, Maharashtra, India.

出版信息

Indian J Med Microbiol. 2023 Jan-Feb;41:25-27. doi: 10.1016/j.ijmmb.2022.12.003. Epub 2022 Dec 23.

DOI:10.1016/j.ijmmb.2022.12.003

PMID:36870744

Abstract

Patients with lung cancer suffer frequent infections which not only thwart the effect of oncological treatment but also affect overall survival. We present a fatal case where coinfection of Pneumocystis jirovecii and Lophomonas blattarum caused pneumonia in a patient with advanced and treated metastatic adenocarcinoma of lung. Cytomegalovirus (CMV) PCR was positive for the patient. Newer pathogens are not only emerging but also there is an increase in incidence of coinfections. Pneumonia due to coinfection of Pneumocystis jirovecii and Lophomonas blattarum is rare and unusual and requires high degree of suspicion and skill for the diagnosis.

摘要

肺癌患者经常发生感染，这不仅会妨碍肿瘤治疗的效果，还会影响总体生存率。我们报告一例致命病例，一名晚期且已接受治疗的肺转移性腺癌患者发生了耶氏肺孢子菌和蜚蠊披发虫合并感染导致的肺炎。该患者的巨细胞病毒（CMV）聚合酶链反应呈阳性。新出现的病原体不仅在不断涌现，合并感染的发生率也在上升。耶氏肺孢子菌和蜚蠊披发虫合并感染所致的肺炎罕见且不常见，诊断需要高度的怀疑意识和专业技能。