Copenhagen Research Centre for Mental Health - CORE, Mental Health Centre Copenhagen, Copenhagen University Hospital, Gentofte Hospitalsvej 15, 2900 Hellerup, Denmark. [E-mail:
Scand J Work Environ Health. 2023 May 1;49(4):303-308. doi: 10.5271/sjweh.4084. Epub 2023 Mar 5.
Integrating vocational rehabilitation and mental healthcare has shown effects on vocational outcomes during sick leave with common mental disorders. In a previous paper, we showed that a Danish integrated healthcare and vocational rehabilitation intervention (INT) had a surprisingly negative impact on vocational outcomes compared to service as usual (SAU) at 6- and 12-month follow-up. That was also the case with a mental healthcare intervention (MHC) tested in the same study. This article reports the 24-month follow-up results of that same study.
A randomized, parallel-group, three-arm, multi-centre superiority trial was conducted to test the effectiveness of INT and MHC compared to SAU.
In total, 631 persons were randomized. Contrary to our hypothesis, SAU showed faster return to work than both INT [hazard rate (HR) 1.39, P=0.0027] and MHC (HR 1.30, P=0.013) at 24-month follow-up. Overall, no differences were observed regarding mental health and functional level. Compared to SAU, we observed some health benefits of MHC, but not INT, at 6-month follow-up but not thereafter, and lower rates of employment at all follow-ups. Since implementation problems might explain the results of INT, we cannot conclude that INT is no better that SAU. The MHC intervention was implemented with good fidelity and did not improve return to work.
This trial does not support the hypothesis that INT lead to faster return to work. However, implementation failure may explain the negative results.
将职业康复与精神卫生保健相结合,已显示出对常见精神障碍病假期间职业结果的影响。在之前的一篇论文中,我们表明与常规服务(SAU)相比,丹麦的综合医疗保健和职业康复干预(INT)在 6 个月和 12 个月的随访中对职业结果产生了出乎意料的负面影响。在同一研究中测试的精神保健干预(MHC)也是如此。本文报告了该相同研究的 24 个月随访结果。
一项随机、平行分组、三臂、多中心优势试验,旨在测试 INT 和 MHC 与 SAU 相比的有效性。
共有 631 人被随机分配。与我们的假设相反,SAU 在 24 个月的随访中比 INT(危险比 [HR] 1.39,P=0.0027)和 MHC(HR 1.30,P=0.013)更快地恢复工作。总体而言,在心理健康和功能水平方面没有差异。与 SAU 相比,我们在 6 个月的随访中观察到 MHC 的一些健康益处,但不是 INT,此后没有观察到,所有随访的就业率都较低。由于实施问题可能解释了 INT 的结果,我们不能得出 INT 不比 SAU 更好的结论。MHC 干预的实施具有良好的保真度,并没有改善工作回归。
本试验不支持 INT 导致更快恢复工作的假设。然而,实施失败可能解释了负面结果。