Division of Critical Care Medicine, Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, 619 19th Street South, JT 845, Birmingham, AL 35249, USA.
Division of Critical Care Medicine, University of Alabama at Birmingham, 901 19th Street South, PBMR 302, Birmingham, AL 35294, USA; Division of Molecular and Translational Biomedicine, Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, 901 19th Street South, PBMR 302, Birmingham, AL 35294, USA.
Anesthesiol Clin. 2023 Mar;41(1):283-301. doi: 10.1016/j.anclin.2022.10.008.
Massive trauma remains the leading cause of mortality among people aged younger than 45 years. In this review, we discuss the initial care and diagnosis of trauma patients followed by a comparison of resuscitation strategies. We discuss various strategies including use of whole blood and component therapy, examine viscoelastic techniques for management of coagulopathy, and consider the benefits and limitations of the resuscitation strategies and consider a series of questions that will be important for researchers to answer to provide the best and most cost-effective therapy for severely injured patients.
大量创伤仍然是 45 岁以下人群死亡的主要原因。在这篇综述中,我们讨论了创伤患者的初步治疗和诊断,然后比较了复苏策略。我们讨论了各种策略,包括使用全血和成分治疗,检查用于凝血功能障碍管理的黏弹性技术,并考虑了复苏策略的利弊,并考虑了一系列问题,这些问题对于研究人员回答提供最佳和最具成本效益的治疗严重受伤患者非常重要。