全血输注在创伤中的应用。
The Use of Whole Blood Transfusion in Trauma.
作者信息
Hanna Mary, Knittel Justin, Gillihan Jason
机构信息
Department of Anesthesiology and Pain Medicine, University of Ottawa, The Ottawa Hospital, Ottawa, ON, CA K1S5W1 Canada.
Department of Anesthesiology, Washington University School of Medicine, Campus Box 8054, 600 S Euclid Ave, St Louis, MO 63110 USA.
出版信息
Curr Anesthesiol Rep. 2022;12(2):234-239. doi: 10.1007/s40140-021-00514-w. Epub 2022 Jan 17.
Abstract
PURPOSE OF REVIEW
This review illustrates the current benefits, limitations, ongoing research, and future paths for Low Titer O Whole Blood compared to Component Therapy in massive transfusion for trauma patients.
RECENT FINDINGS
Many studies show that compared to Component Therapy, Low Titer O Whole Blood transfusion is associated with better patient outcomes and simplified transfusion logistics among others. There are, however, issues with cost, supply/demand and handling of Whole Blood that limit its use, but experience in the military setting has shown that these limitations can be easily overcome.
SUMMARY
The use of Whole Blood has increased in the civilian trauma population and there is a growing body of evidence to support its current use. More research looking at Whole Blood in females of child-bearing age, pediatric populations, and cold-stored platelets is underway.
摘要
综述目的
本综述阐述了与成分输血相比，低滴度O型全血在创伤患者大量输血中的当前益处、局限性、正在进行的研究以及未来方向。
最新发现
许多研究表明，与成分输血相比，输注低滴度O型全血与更好的患者预后以及简化输血流程等相关。然而，全血在成本、供需和处理方面存在问题，限制了其使用，但军事环境中的经验表明，这些局限性很容易克服。
总结
全血在 civilian trauma population 中的使用有所增加，并且有越来越多的证据支持其目前的使用。正在进行更多关于育龄女性、儿科人群和冷藏血小板中全血的研究。 （注：“civilian trauma population”直译为“平民创伤人群”，可能表述不太准确，可根据上下文进一步优化）
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本文引用的文献
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Transfusion. 2021 Jun;61(6):1966-1971. doi: 10.1111/trf.16380. Epub 2021 Mar 29.
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Low titer group O whole blood resuscitation: Military experience from the point of injury.低滴度 O 型全血复苏：损伤部位的军事经验。
J Trauma Acute Care Surg. 2020 Oct;89(4):834-841. doi: 10.1097/TA.0000000000002863.
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