Research and Development Unit, Parc Sanitari Sant Joan de Déu, CIBERSAM, ISCIII, Barcelona, Spain.
Department of Physical Medicine and Rehabilitation, Lariboisière-Fernand Widal Hospital, AP-HP, University Paris Cité, Paris, France.
J Cachexia Sarcopenia Muscle. 2023 Apr;14(2):1130-1138. doi: 10.1002/jcsm.13215. Epub 2023 Mar 5.
There are no data on the association between leisure-time physical activity (LTPA) and sarcopenia in older adults from low- and middle-income countries (LMICs). This study aimed to investigate the association between LTPA and sarcopenia in individuals aged ≥65 years living in six LMICs.
Cross-sectional data from the Study on Global AGEing and Adult Health (China, Ghana, India, Mexico, Russia and South Africa) were analysed. Sarcopenia referred to the presence of both low skeletal muscle mass and weak handgrip strength. LTPA was assessed using the Global Physical Activity Questionnaire and was analysed as a dichotomized variable [high LTPA (>150 min/week of moderate-to-vigorous LTPA) or low LTPA (≤150 min/week)]. Multivariable logistic regression analysis was conducted to assess associations.
There were 14 585 individuals included in this study [mean (SD) age 72.6 (11.5) years; 55.0% women]. The prevalence of high LTPA and sarcopenia was 8.9% and 12.0%, respectively. After adjusting for potential confounders, low LTPA was significantly associated with higher odds for sarcopenia [prevalence odds ratio (POR) = 1.85, 95% confidence interval (CI) = 1.29-2.65] compared with high LTPA. Significant associations were found in women (POR = 3.22, 95% CI = 1.82-5.68) but not in men (POR = 1.52, 95% CI = 0.99-2.35).
A positive and significant association between low LTPA and sarcopenia was found among older adults from LMICs. The promotion of LTPA among older adults in LMICs may aid in the prevention of sarcopenia, especially among females, pending future longitudinal research.
在来自中低收入国家(LMICs)的老年人中,关于休闲时间体力活动(LTPA)与肌肉减少症之间的关联尚无数据。本研究旨在调查 6 个 LMIC 中≥65 岁人群中 LTPA 与肌肉减少症之间的关联。
使用全球老龄化与成人健康研究(中国、加纳、印度、墨西哥、俄罗斯和南非)的横断面数据进行分析。肌肉减少症是指存在低骨骼肌量和弱握力。使用全球体力活动问卷评估 LTPA,并将其作为二分变量进行分析[高 LTPA(>150 分钟/周的中等到剧烈体力活动)或低 LTPA(≤150 分钟/周)]。进行多变量逻辑回归分析以评估相关性。
本研究共纳入 14585 人[平均(标准差)年龄 72.6(11.5)岁;55.0%为女性]。高 LTPA 和肌肉减少症的患病率分别为 8.9%和 12.0%。在调整了潜在混杂因素后,与高 LTPA 相比,低 LTPA 与肌肉减少症的患病风险显著增加相关[患病比值比(POR)=1.85,95%置信区间(CI)=1.29-2.65]。在女性中发现了显著相关性(POR=3.22,95%CI=1.82-5.68),但在男性中未发现相关性(POR=1.52,95%CI=0.99-2.35)。
在来自 LMICs 的老年人中,低 LTPA 与肌肉减少症之间存在显著的正相关。在 LMIC 中,促进老年人进行 LTPA 可能有助于预防肌肉减少症,特别是在女性中,有待未来的纵向研究进一步证实。