Liu Yujie, Tang Zhengyan, Hou Xiao, Yuan Yaqing, Hsu Yunli, Lin Jinxia, Liu Jingmin
Division of Sports Science and Physical Education, Tsinghua University, Beijing 100084, China.
Department of Physical Education, Southeast University, Nanjing 210096, China.
Healthcare (Basel). 2025 Jan 27;13(3):251. doi: 10.3390/healthcare13030251.
This study aimed to explore the independent and joint associations of daily sitting time and leisure-time physical activity (LTPA) with sarcopenia among older adults.
The participants were 847 community-dwelling adults aged 60 or older from Beijing and Shanghai, China. Sarcopenia was diagnosed based on the criteria established by the Asian Working Group for Sarcopenia (2019). Daily sitting time and LTPA were self-reported using the Physical Activity Scale for the Elderly (PASE). Logistics regression models were used to explore the associations between daily sitting time, LTPA, and sarcopenia. To examine joint associations, participants were classified based on daily sitting time and LTPA levels. Final models were adjusted for sociodemographic variables, lifestyle factors, and chronic conditions.
Prolonged sitting time and insufficient LTPA were independently associated with higher odds of sarcopenia. Among insufficiently active participants, sitting for 1-2 h, 2-4 h, and more than 4 h per day was associated with 5.52-fold (95% CI: 1.13-26.83), 6.69-fold (95% CI: 1.33-33.59), and 12.82-fold (95% CI: 2.75-59.85) increased odds of sarcopenia, respectively, compared to sitting for less than 1 h. For those meeting the physical activity guideline (≥150 min of LTPA per week), only sitting for more than 4 h per day was significantly associated with higher odds of sarcopenia (OR: 7.25, 95% CI: 1.99-26.36).
Prolonged sedentary behavior was associated with increased odds of sarcopenia. The higher odds of sarcopenia associated with more than 4 h daily sitting may not be offset by achieving the recommended levels of physical activity.
本研究旨在探讨老年人每日久坐时间和休闲体力活动（LTPA）与肌肉减少症之间的独立关联和联合关联。
研究对象为来自中国北京和上海的847名60岁及以上的社区居住成年人。肌肉减少症根据亚洲肌肉减少症工作组（2019年）制定的标准进行诊断。每日久坐时间和LTPA通过老年人身体活动量表（PASE）进行自我报告。采用逻辑回归模型探讨每日久坐时间、LTPA与肌肉减少症之间的关联。为了检验联合关联，根据每日久坐时间和LTPA水平对参与者进行分类。最终模型对社会人口统计学变量、生活方式因素和慢性病进行了调整。
久坐时间延长和LTPA不足与肌肉减少症的较高几率独立相关。在活动不足的参与者中，每天久坐1 - 2小时、2 - 4小时和超过4小时与肌肉减少症几率增加分别为5.52倍（95%CI：1.13 - 26.83）、6.69倍（95%CI：1.33 - 33.59）和12.82倍（95%CI：2.75 - 59.85），与每天久坐少于1小时相比。对于那些达到身体活动指南（每周LTPA≥150分钟）的人，只有每天久坐超过4小时与肌肉减少症的较高几率显著相关（OR：7.25，95%CI：1.99 - 26.36）。
久坐行为延长与肌肉减少症几率增加有关。每日久坐超过4小时与肌肉减少症较高几率相关，可能无法通过达到推荐的身体活动水平来抵消。
