[实验中分离蜱传脑炎病毒裂解疫苗和全病毒疫苗及其免疫原性和抗原性特征]
[Isolation of split and whole-virion tick-borne encephalitis vaccines in an experiment and the characteristics of their immunogenic and antigenic properties].
作者信息
Osipova E G, Solianik R G, Fedorov Iu V, Tymchishin P N
出版信息
Zh Mikrobiol Epidemiol Immunobiol. 1987 Aug(8):50-3.
PMID:3687295
Abstract
The split preparation, obtained by the treatment of purified and concentrated tick-borne encephalitis virus with 0.5% Tween-80 and ether and inactivated with formalin at a minimal concentration of 1:10,000, did not contain the active virus. After the removal of the detergent, the preparation retained its antigenic and immunogenic properties.
摘要
将纯化浓缩的蜱传脑炎病毒用0.5%吐温-80和乙醚处理，并用最低浓度为1:10000的福尔马林灭活后得到的裂解制剂不含活性病毒。去除去污剂后，该制剂保留了其抗原性和免疫原性。
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