Liapustin V N, Pivanova G P, Karavanov A S, Lashkevich V A
Vopr Virusol. 1991 Nov-Dec;36(6):498-500.
A comparative assessment of the protective properties of virion (VA) and nonvirion ("soluble") (NA) antigens of tick-borne encephalitis virus prepared as inactivated samples close in their parameters to vaccine preparations was carried out. The NA in the preparations free from VA or containing only trace, nonprotective amounts of it, was shown to have significantly lower protective properties than VA and exerted no booster effect on the protective activity when added to VA preparations.
对蜱传脑炎病毒的病毒体(VA)抗原和非病毒体(“可溶性”)(NA)抗原的保护特性进行了比较评估,这些抗原制成的灭活样品在参数上与疫苗制剂相近。在不含VA或仅含有微量非保护性VA的制剂中,NA的保护特性明显低于VA,并且当添加到VA制剂中时,对保护活性没有增强作用。