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一名患有神经功能缺损的青少年男性因结核病因导致胸腰段硬膜外脓肿的罕见病例。

A Rare Case of Thoracolumbar Epidural Abscess with Tuberculous Etiology in an Adolescent Male with Neurological Deficit.

作者信息

Ambulgekar Rajesh K, Iqbal Zafar, Masne Pratik

机构信息

Department of Orthopaedics, Dr. Shankarrao Chavan Government Medical College, Nanded, Maharashtra, India.

出版信息

J Orthop Case Rep. 2022 Sep;12(9):98-101. doi: 10.13107/jocr.2022.v12.i09.3336.

DOI:10.13107/jocr.2022.v12.i09.3336
PMID:36873335
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9983397/
Abstract

INTRODUCTION

Spinal epidural abscess (SEA) refers to collection of infection of the epidural space due to various etiologies. Tuberculosis (TB) of the spine is one of the important causes of SEA. Patient with SEA usually presents with history of fever, back pain, difficulty in walking, and neurological weakness. Magnetic resonance imaging (MRI) is the initial modality for diagnosis and it can be confirmed by examination of abscess for microorganism growth. It can be treated by laminectomy and decompression which helps to drain out the pus and relive the compression on the cord.

CASE REPORT

A 16-year-old male, student by profession, presented with a history of low back pain and progressive difficulty in walking for the past 12 days and lower limb weakness for the past 8 days associated with fever, generalized weakness, and malaise. Computed tomography brain and whole spine showed no significant changes MRI left facetal joint of L3 L4 vertebrae infective arthritis with abnormal soft-tissue collection in the posterior epidural region extending from D11-L5 vertebrae causing compression on the thecal sac, cauda equine nerve roots, and represents infective abscess with abnormal soft-tissue collection in the posterior paraspinal region and left psoas muscles representing infective abscess. Patient was taken for emergency decompression with clearance of abscess through posterior approach. Laminectomy was done extending from D11 TO L5 vertebrae and thick pus was drained through multiple pockets. Samples pus and soft tissue were sent for investigation. Pus culture ZN and Gram's stain did not show growth of any organism, but GeneXpert was positive for growth of Mycobacterium tuberculosis. Patient was registered under RNTCP program and anti TB drugs were started as per the weight scale. Sutures were removed on post-operative day 12 and neurological evaluation was done for any signs of improvement. Patient showed improvement of power in both lower limb; power 5/5 on the right lower limb whereas 4/5 in the left lower limb. Patient also had improvements in other symptoms and has no complaints of back ache and malaise at discharge.

CONCLUSION

Tuberculous thoracolumbar epidural abscess is a rare disease with potential to cause lifelong vegetative state if diagnosis and treatment is not done promptly. Surgical decompression by unilateral laminectomy and evacuation of collection is both diagnostic and therapeutic.

摘要

引言

脊柱硬膜外脓肿(SEA)是指由于各种病因导致硬膜外间隙感染积聚。脊柱结核是SEA的重要病因之一。SEA患者通常有发热、背痛、行走困难和神经功能无力的病史。磁共振成像(MRI)是诊断的初始方法,可通过检查脓肿以确定微生物生长来确诊。可通过椎板切除术和减压治疗,这有助于排出脓液并减轻脊髓压迫。

病例报告

一名16岁男性,职业为学生,有腰痛病史,在过去12天里行走困难逐渐加重,在过去8天里下肢无力,伴有发热、全身无力和不适。计算机断层扫描脑部和全脊柱未见明显异常。MRI显示L3 - L4椎体左侧小关节感染性关节炎,硬膜后区域有异常软组织积聚,从D11延伸至L5椎体,压迫硬膜囊、马尾神经根,并在椎旁后区域和左侧腰大肌有异常软组织积聚,代表感染性脓肿。患者接受了紧急减压手术,通过后路清除脓肿。从D11至L5椎体进行椎板切除术,通过多个腔隙引流浓稠脓液。采集脓液和软组织样本进行检查。脓液培养、抗酸染色(ZN)和革兰氏染色均未显示任何微生物生长,但GeneXpert检测显示结核分枝杆菌生长呈阳性。患者在国家结核病控制规划(RNTCP)项目中登记,并根据体重标准开始使用抗结核药物。术后第12天拆线,并对患者进行神经功能评估以观察是否有改善迹象。患者双下肢肌力有所改善;右下肢肌力为5/5,左下肢肌力为4/5。患者的其他症状也有所改善,出院时无背痛和不适主诉。

结论

结核性胸腰段硬膜外脓肿是一种罕见疾病,如果不及时诊断和治疗,有可能导致终身植物人状态。通过单侧椎板切除术和清除积脓进行手术减压具有诊断和治疗双重作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/790e/9983397/e7c2de6eaee7/JOCR-12-98-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/790e/9983397/882d4dd0853b/JOCR-12-98-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/790e/9983397/e7c2de6eaee7/JOCR-12-98-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/790e/9983397/882d4dd0853b/JOCR-12-98-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/790e/9983397/e7c2de6eaee7/JOCR-12-98-g003.jpg

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