Kao Andrew S, Cramer-Bour Cassondra, Kupsky William, Soubani Ayman O
Wayne State University School of Medicine, 540 E. Canfield St, Detroit, 48201, United States.
Detroit Medical Center, Department of Pulmonary and Critical Care Medicine, 3990 John R- 3 Hudson, Detroit, MI, 48201, United States.
Med Mycol Case Rep. 2023 Feb 19;40:5-7. doi: 10.1016/j.mmcr.2023.02.004. eCollection 2023 Jun.
species manifests as an opportunistic infection with intrinsic resistance to most antifungals. We present a case of a 63-year-old male with myelodysplasia who received allogeneic stem cell transplantation and presented with endophthalmitis as the initial manifestation of invasive fusariosis that progressed to a fatal outcome despite combined intravitreal and systemic antifungal therapies. We urge clinicians to consider this complication of fusarium infection especially with the widespread use of antifungal prophylaxis that may incur selection of more resistant, invasive fungal species.
该菌种表现为机会性感染，对大多数抗真菌药物具有固有耐药性。我们报告一例63岁患有骨髓增生异常的男性病例，该患者接受了异基因干细胞移植，以眼内炎作为侵袭性镰刀菌病的初始表现，尽管采用了玻璃体内和全身抗真菌联合治疗，但病情仍发展至致命结局。我们敦促临床医生考虑这种镰刀菌感染并发症，尤其是在广泛使用抗真菌预防措施可能导致选择更具耐药性的侵袭性真菌菌种的情况下。
