Chen Junni, Zhang Shuai, Chen Jiawei
Department of Radiation Oncology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan, China.
Front Oncol. 2023 Feb 17;13:1092868. doi: 10.3389/fonc.2023.1092868. eCollection 2023.
Esophageal cancer is prone to distant metastasis, and the prognosis is very poor; the occurrence of intestinal metastasis is extremely rare, with atypical clinical manifestations. We report a case of rectal metastasis after surgery for esophageal squamous cell carcinoma. The patient was a 63-year-old male who was admitted to the hospital due to progressive dysphagia. He was diagnosed with moderately differentiated esophageal squamous cell carcinoma after the surgery. He was not treated with chemoradiotherapy after surgery and had recurrent blood in his stool at 9 months post-surgery; rectal metastasis of esophageal squamous carcinoma was diagnosed based on postoperative pathology. Because the patient had a positive rectal margin, we used adjuvant chemoradiotherapy and carrelizumab immunotherapy, achieving very good short-term efficacy. The patient is currently in a state of tumor-free survival and is still being closely followed up and treated. Through this case report, we hope to deepen understanding of rare metastasis of esophageal squamous cell carcinoma and actively promote local radiotherapy plus chemotherapy and immunotherapy to improve survival.
食管癌易于发生远处转移，预后很差；发生肠转移极为罕见，临床表现不典型。我们报告1例食管鳞状细胞癌术后直肠转移的病例。患者为63岁男性，因进行性吞咽困难入院。术后诊断为中分化食管鳞状细胞癌。术后未接受放化疗，术后9个月出现便血；根据术后病理诊断为食管鳞状细胞癌直肠转移。由于患者直肠切缘阳性，我们采用了辅助放化疗及卡瑞利珠单抗免疫治疗，取得了很好的短期疗效。患者目前处于无瘤生存状态，仍在密切随访及治疗中。通过本病例报告，我们希望加深对食管鳞状细胞癌罕见转移的认识，并积极推广局部放疗加化疗及免疫治疗以提高生存率。
