Kibret Anteneh Ayelign, Wolde Haileab Fekadu, Moges Abebe Muche, Aragie Hailu, Teferi Ephrem Tafesse, Assefa Yohannes Awoke, Melese Endalkachew Belayneh, Melesse Mequanint, Worku Yilkal Belete, Belay Daniel Gashaneh, Molla Meseret Derbew, Adugna Dagnew Getnet
Department of Human Anatomy, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Front Pain Res (Lausanne). 2023 Feb 17;3:1061239. doi: 10.3389/fpain.2022.1061239. eCollection 2022.
Globally, cancer is the second leading cause of death and was responsible for 9.6 million deaths in 2018. Worldwide, 2 million people experience pain every day, and cancer pain is one of the major neglected public health problems, especially in Ethiopia. Despite reporting the burden and risk factors of cancer pain as a principal importance, there are limited studies. Therefore, this study aimed to assess the prevalence of cancer pain and its associated factors among adult patients evaluated at the oncology ward in the University of Gondar Comprehensive Specialized Hospital, northwest Ethiopia.
An institution-based cross-sectional study was conducted from 1 January to 31 March 2021. A systematic random sampling technique was used to select the total sample size of 384 patients. Data were collected using pretested and structured interviewer-administered questionnaire. Bivariate and multivariate logistic regression models were fitted to identify the factors associated with cancer pain among patients with cancer. An adjusted odds ratio (AOR) with a 95% CI was computed to determine the level of significance.
A total of 384 study participants were involved, with a response rate of 97.5%. The proportion of cancer pain was found to be 59.9% (95% CI 54.8-64.8). The odds of cancer pain were escalated by anxiety (AOR = 2.52, 95% CI 1.02-6.19), patients with hematological cancer (AOR = 4.68, 95% CI 1.30-16.74), gastrointestinal cancer (AOR = 5.15, 95% CI 1.45-18.2), and stages III and IV (AOR = 14.3, 95% CI 3.20-63.7).
The prevalence of cancer pain among adult patients with cancer in northwest Ethiopia is relatively high. Variables such as anxiety, types of cancer, and stage of cancer had a statistically significant association with cancer pain. Hence, to advance the management of pain, it is better to create more awareness regarding cancer-related pain and provide palliative care early on in the diagnosis of the disease.
在全球范围内，癌症是第二大致死原因，2018年造成了960万人死亡。在世界范围内，每天有200万人遭受疼痛折磨，癌症疼痛是主要被忽视的公共卫生问题之一，在埃塞俄比亚尤其如此。尽管将癌症疼痛的负担和风险因素报告为至关重要，但相关研究有限。因此，本研究旨在评估埃塞俄比亚西北部贡德尔大学综合专科医院肿瘤病房接受评估的成年患者中癌症疼痛的患病率及其相关因素。
于2021年1月1日至3月31日进行了一项基于机构的横断面研究。采用系统随机抽样技术选取了384名患者作为总样本量。使用预先测试并结构化的访谈者管理问卷收集数据。采用二元和多元逻辑回归模型来确定癌症患者中与癌症疼痛相关的因素。计算调整后的优势比（AOR）及95%置信区间以确定显著性水平。
共有384名研究参与者，应答率为97.5%。发现癌症疼痛的比例为59.9%（95%置信区间54.8 - 64.8）。焦虑（AOR = 2.52，95%置信区间1.02 - 6.19）、血液系统癌症患者（AOR = 4.68，95%置信区间1.30 - 16.74）、胃肠道癌症患者（AOR = 5.15，95%置信区间1.45 - 18.2）以及III期和IV期患者（AOR = 14.3，95%置信区间3.20 - 63.7）会增加癌症疼痛的几率。
埃塞俄比亚西北部成年癌症患者中癌症疼痛的患病率相对较高。焦虑、癌症类型和癌症分期等变量与癌症疼痛存在统计学上的显著关联。因此，为了改善疼痛管理，最好提高对癌症相关疼痛的认识，并在疾病诊断早期提供姑息治疗。
