Sakaki S, Ohta S, Kuwabara H, Shiraishi M
Department of Neurosurgery, Ehime University Medical School, Japan.
Acta Neurochir (Wien). 1987;88(3-4):87-94. doi: 10.1007/BF01404143.
In a series of 177 patients with ruptured supratentorial aneurysms we studied retrospectively the results of early and delayed operation without aggressive removal of subarachnoid blood clots but ventricular and cisternal drainage. The early and delayed groups were comparable demographically and neurologically. The overall results for the early group were a good outcome in 65%, poor outcome in 10% and death in 24%, compared to 53, 20 and 27% respectively in the delayed group. Thus, patients with an early operation and CSF drainage had better results. Permanent ischaemic neurological deficits due to cerebral vasospasm accounted for the poor outcome in 10 and 21% of the patients in the early and delayed groups, respectively and rebleeding accounted for the poor outcome in 5 and 10% in the early and delayed groups respectively. The mean amount of haemoglobin in the cerebrospinal fluid from cisternal drainage was 6.4 g, corresponding to about 40 ml of whole blood, during the 12-day period after SAH. The level was higher in patients with larger subarachnoid clots or with symptomatic vasospasm than in those with smaller clots or without such vasospasm. Early operation combined with ventricular and cisternal drainage is considered to be a useful surgical method for patient with a ruptured aneurysm.
在一组177例幕上动脉瘤破裂患者中,我们回顾性研究了早期手术和延迟手术的结果,手术中未积极清除蛛网膜下腔血凝块,而是进行了脑室和脑池引流。早期手术组和延迟手术组在人口统计学和神经学方面具有可比性。早期手术组的总体结果是,65%预后良好,10%预后不良,24%死亡;而延迟手术组的相应比例分别为53%、20%和27%。因此,早期手术并进行脑脊液引流的患者预后更好。早期手术组和延迟手术组分别有10%和21%的患者因脑血管痉挛出现永久性缺血性神经功能缺损,早期手术组和延迟手术组分别有5%和10%的患者因再出血导致预后不良。蛛网膜下腔出血后12天内,脑池引流脑脊液中的血红蛋白平均含量为6.4 g,相当于约40 ml全血。蛛网膜下腔血凝块较大或有症状性血管痉挛的患者,其血红蛋白水平高于血凝块较小或无此类血管痉挛的患者。早期手术联合脑室和脑池引流被认为是治疗动脉瘤破裂患者的一种有效手术方法。