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Roux-en-Y胃旁路术后的边缘性溃疡及相关危险因素

Marginal ulcers and associated risk factors after Roux-en-Y gastric bypass.

作者信息

Wynn Matthew, Tecson Kristen M, Provost David

机构信息

Department of Surgery, Baylor Scott & White Medical Center - Temple, Temple, Texas.

Baylor Scott & White Research Institute, Dallas, Texas.

出版信息

Proc (Bayl Univ Med Cent). 2022 Nov 3;36(2):171-177. doi: 10.1080/08998280.2022.2137362. eCollection 2023.

Abstract

As the prevalence of morbid obesity continues to climb in America, so does the popularity of the Roux-en-Y gastric bypass (RYGB) to achieve weight loss goals; however, a long-term risk of RYGB is marginal ulceration, which requires urgent surgery if perforated. We sought to identify characteristics associated with elective vs urgent presentation for marginal ulcer following RYGB. Retrospective data for consecutive cases with marginal ulcers that required surgical intervention from May 2016 to February 2021 were queried from our institution's bariatric database, and differences in patient characteristics and clinical course were assessed according to presentation. Forty-three patients underwent surgery for marginal ulcer during the study timeframe. Twenty-four (56%) patients presented electively and were treated with resection of the gastroenterostomy and reanastomosis; the remaining 19 (44%) presented urgently with perforation and were treated with omental patch repair. Demographics, comorbidities, and medications were similar between groups. Patients with urgent presentations were less likely to have bleeds (0% vs. 33%,  = 0.0056) and strictures (16% vs. 46%,  = 0.0368), but were more likely to require admission to the intensive care unit (32% vs. 4%,  = 0.0325) and have a longer median length of stay (2 vs. 5 days,  < 0.0001). Bariatric surgeons must properly counsel patients about the risk of marginal ulcer development to prevent dangerous perforation, intensive care unit stays, and long hospitalizations.

摘要

随着美国病态肥胖的患病率持续攀升,用于实现减重目标的 Roux-en-Y 胃旁路术(RYGB)也越来越受欢迎;然而,RYGB 的一个长期风险是边缘性溃疡,如果发生穿孔则需要紧急手术。我们试图确定与 RYGB 术后边缘性溃疡的择期与紧急就诊相关的特征。从我们机构的肥胖症数据库中查询了 2016 年 5 月至 2021 年 2 月期间因边缘性溃疡需要手术干预的连续病例的回顾性数据,并根据就诊情况评估了患者特征和临床过程的差异。在研究期间,43 例患者接受了边缘性溃疡手术。24 例(56%)患者择期就诊,接受了胃肠吻合口切除和重新吻合术治疗;其余 19 例(44%)患者因穿孔紧急就诊,接受了网膜补片修补术治疗。两组患者的人口统计学、合并症和用药情况相似。紧急就诊的患者出血(0% 对 33%,P = 0.0056)和狭窄(16% 对 46%,P = 0.0368)的可能性较小,但更有可能需要入住重症监护病房(32% 对 4%,P = 0.0325),且中位住院时间更长(2 天对 5 天,P < 0.0001)。肥胖症外科医生必须就边缘性溃疡发生的风险向患者提供适当的咨询,以防止危险的穿孔、重症监护病房住院和长时间住院。

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Marginal ulcers and associated risk factors after Roux-en-Y gastric bypass.Roux-en-Y胃旁路术后的边缘性溃疡及相关危险因素
Proc (Bayl Univ Med Cent). 2022 Nov 3;36(2):171-177. doi: 10.1080/08998280.2022.2137362. eCollection 2023.

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