Departamento de Química Analítica y Análisis Instrumental, Facultad de Ciencias, Universidad Autónoma de Madrid. Avda. Francisco Tomás y Valiente, Avda. Francisco Tomás y Valiente, 7. E-28049, Madrid, Spain.
Mikrochim Acta. 2023 Mar 6;190(4):115. doi: 10.1007/s00604-023-05690-6.
An electrochemical sensor has been developed, by modifying screen-printed carbon devices (SPCE) with photochemically synthesized gold nanoparticles (AuNP), to determine benzyl alcohol, a preservative widely used in the cosmetic industry. To obtain the AuNP with the best properties for electrochemical sensing applications, the photochemical synthesis was optimized using chemometric tools. A response surface methodology based on central composite design was used to optimize the synthesis conditions, as irradiation time, and the concentrations of metal precursor and the capping/reducing agent (poly(diallyldimethylammonium) chloride, PDDA). The anodic current of benzyl alcohol on SPCE modified with the AuNP was used as response of the system. The best electrochemical responses were obtained using the AuNP generated by irradiating for 18 min a 7.20 [Formula: see text] 10 mol L AuCl-1.7% PDDA solution. The AuNP were characterized by transmission electron microscopy, cyclic voltammetry and dynamic light scattering. The nanocomposite-based sensor formed by the optimal AuNP (AuNP@PDDA/SPCE) was used to determine benzyl alcohol by linear sweep voltammetry in 0.10 mol L KOH. The anodic current at + 0.017 ± 0.003 V (vs. AgCl) was used as analytical signal. Detection limit obtained under these conditions was 2.8 µg mL. The AuNP@PDDA/SPCE was applied to determine benzyl alcohol in cosmetic samples.
电化学传感器已被开发出来，通过用光电化学合成的金纳米粒子（AuNP）修饰丝网印刷碳设备（SPCE），以测定苯甲醇，一种广泛用于化妆品行业的防腐剂。为了获得最适合电化学传感应用的 AuNP，使用化学计量学工具优化了光电化学合成。基于中心复合设计的响应面法用于优化合成条件，如辐照时间以及金属前体和封端/还原试剂（聚二烯丙基二甲基氯化铵，PDDA）的浓度。修饰有 AuNP 的 SPCE 上苯甲醇的阳极电流被用作系统的响应。使用在 7.20 [Formula: see text] 10-1 mol L AuCl-1.7% PDDA 溶液中辐照 18 min 生成的 AuNP 可获得最佳的电化学响应。通过透射电子显微镜、循环伏安法和动态光散射对 AuNP 进行了表征。基于纳米复合材料的传感器由最佳的 AuNP（AuNP@PDDA/SPCE）组成，通过在 0.10 mol L KOH 中线性扫描伏安法用于测定苯甲醇。在 + 0.017 ± 0.003 V（相对于 AgCl）处的阳极电流被用作分析信号。在这些条件下获得的检测限为 2.8 µg mL。AuNP@PDDA/SPCE 用于测定化妆品样品中的苯甲醇。
