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先天性巨细胞病毒感染患儿的尿液和唾液病毒载量。

Urine and Saliva Viral Load in Children with Congenital Cytomegalovirus Infection.

机构信息

Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama, USA.

出版信息

J Pediatric Infect Dis Soc. 2023 Apr 28;12(4):230-233. doi: 10.1093/jpids/piad013.

DOI:10.1093/jpids/piad013
PMID:36879401
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10146932/
Abstract

Viral load in infant saliva and urine was assessed to predict sensorineural hearing loss (SNHL) in children with congenital cytomegalovirus infection. Viral load was higher in symptomatic infants. Viral load in asymptomatic children with and without SNHL did not differ. Congenital cytomegalovirus infection viral load in urine and saliva does not predict hearing loss.

摘要

评估婴儿唾液和尿液中的病毒载量，以预测先天性巨细胞病毒感染儿童的感音神经性听力损失（SNHL）。有症状的婴儿病毒载量较高。无症状儿童中 SNHL 与无 SNHL 的病毒载量无差异。先天性巨细胞病毒感染的尿液和唾液病毒载量不能预测听力损失。

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本文引用的文献

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J Med Virol. 2022 Sep;94(9):4559-4564. doi: 10.1002/jmv.27844. Epub 2022 May 14.
2
Prevalence and Clinical Manifestations of Congenital Cytomegalovirus Infection in a Screening Program in Madrid (PICCSA Study).马德里筛查项目中先天性巨细胞病毒感染的流行率和临床表现（PICCSA 研究）。
Pediatr Infect Dis J. 2020 Nov;39(11):1050-1056. doi: 10.1097/INF.0000000000002808.
3
Feasible alternatives to DBS in the retrospective diagnosis of congenital cytomegalovirus infection.在回顾性诊断先天性巨细胞病毒感染中，DBS 的可行替代方法。
J Clin Virol. 2020 Aug;129:104504. doi: 10.1016/j.jcv.2020.104504. Epub 2020 Jun 10.
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Congenital Cytomegalovirus Infection.先天性巨细胞病毒感染。
J Infect Dis. 2020 Mar 5;221(Suppl 1):S9-S14. doi: 10.1093/infdis/jiz446.
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Primary cytomegalovirus (CMV) infection in pregnancy: Diagnostic value of CMV PCR in saliva compared to urine at birth.孕妇原发性巨细胞病毒（CMV）感染：唾液 CMV-PCR 与出生时尿液相比的诊断价值。
J Clin Virol. 2019 Aug;117:33-36. doi: 10.1016/j.jcv.2019.05.015. Epub 2019 May 31.
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