Sağlam Gonca, Ergül Emine Esra
Department of Physical Medicine and Rehabilitation, Karadeniz Technical University Faculty of Medicine, Trabzon, Türkiye.
Department of Physical Medicine and Rehabilitation, Erzincan Binali Yıldırım University Mengücek Gazi Training and Research Hospital, Erzincan, Türkiye.
Arch Rheumatol. 2022 Sep 20;37(4):559-565. doi: 10.46497/ArchRheumatol.2022.9586. eCollection 2022 Dec.
This study aims to investigate coronaphobia and physical activity levels in patients with rheumatoid arthritis (RA).
Between December 2021 and February 2022, a total of 68 RA patients (11 males, 57 females; mean age: 48.3±10.1 years; range, 29 to 78 years) and 64 age- and sex-matched healthy individuals (4 males, 60 females; mean age: 47.9±10.2 years; range, 23 to 70 years) were included in this cross-sectional study. Demographic, physical, lifestyle, and medical characteristics of all participants were recorded. The COVID-19 Phobia Scale (C19PS) and the International Physical Activity Questionnaire-Short Form (IPAQ-SF) were administered to all participants. The RA patients were divided into two groups as: patients treated with biological and non-biological agents. The Disease Activity Score-28 (DAS28) and Clinical Disease Activity Index (CDAI) were used to measure disease activity.
The total and subgroup scores of the C19P-S were found to be statistically significantly higher in both the biological and non-biological RA groups than in the control group (p=0.001). However, there was no statistically significant difference between the RA groups in terms of total and subgroup C19P-S scores. The mean IPAQ score was significantly lower in the RA group using biological drugs than in the control group (p=0.002). A significant correlation was found between DAS28 and total C19P-S scores (r:0.63, p<0.05), and CDAI and total C19P-S scores (r:0.79, p<0.05).
Patients with RA have an increased risk of coronaphobia and disease activity is correlated with coronaphobia. Patients treated with biological agents seem to have lower activity levels compared to other RA patients and healthy controls. These results should be considered in the management of RA during COVID-19 pandemic and preventive intervention strategies should be formulated to cope with coronaphobia.
本研究旨在调查类风湿关节炎(RA)患者的新冠恐惧症及身体活动水平。
在2021年12月至2022年2月期间,本横断面研究纳入了68例RA患者(11例男性,57例女性;平均年龄:48.3±10.1岁;范围29至78岁)以及64例年龄和性别匹配的健康个体(4例男性,60例女性;平均年龄:47.9±10.2岁;范围23至70岁)。记录了所有参与者的人口统计学、身体、生活方式和医学特征。对所有参与者进行了新冠恐惧症量表(C19PS)和国际身体活动问卷简表(IPAQ-SF)评估。RA患者被分为两组:接受生物制剂和非生物制剂治疗的患者。采用疾病活动评分28(DAS28)和临床疾病活动指数(CDAI)来衡量疾病活动度。
发现生物制剂组和非生物制剂组RA患者的C19P-S总分及亚组得分在统计学上均显著高于对照组(p = 0.001)。然而,RA组之间在C19P-S总分及亚组得分方面无统计学显著差异。使用生物制剂的RA组的IPAQ平均得分显著低于对照组(p = 0.002)。发现DAS28与C19P-S总分之间存在显著相关性(r:0.63,p < 0.05),以及CDAI与C19P-S总分之间存在显著相关性(r:0.79,p < 0.05)。
RA患者患新冠恐惧症的风险增加,且疾病活动度与新冠恐惧症相关。与其他RA患者及健康对照组相比,接受生物制剂治疗的患者似乎活动水平较低。在新冠疫情期间RA的管理中应考虑这些结果,并应制定预防干预策略以应对新冠恐惧症。