Gynaecology and Operating Room, Shanghai University of Traditional Chinese Medicine Taizhou Hospital, Taizhou, Zhejiang, China.
Taizhou Central Hospital, Neurology department, California Baptist University, Zhejiang, China.
Biotechnol Genet Eng Rev. 2024 Apr;40(1):664-677. doi: 10.1080/02648725.2023.2186559. Epub 2023 Mar 7.
There is no consensus on whether acupoint catgut embedding should be widely used as a treatment for hyperlipidemia. Acupoint catgut embedding is also not included in the guidelines for the treatment of hyperlipidemia. The purpose of this study was of two aspects: 1) to review recent research advances in the relationship between acupoint catgut embedding and hyperlipidemia, 2) to make a meta-analysis of the effects of acupoint catgut embedding on hyperlipidemia. We conducted a meta-analysis of studies extracted from PubMed, the Cochrane Library, Embase CNKI, Wanfang Data and VIP to identify randomized controlled trials (RCTs) evaluating the efficacy of acupoint catgut embedding on hyperlipidemia evaluated through screening, inclusion, data extraction and quality assessment. We performed a meta-analysis using Review Manager 5.3 software. A total of 9 RCTs, involving more than 500 adults over 18 years old, were included. Compared with acupoint catgut embedding, drugs resulted in TC [MD = -0.08, 95% CI (-0.20, 0.05), = 0.41, I = 2%], in TG [MD =-0.04, 95% CI (-0.20, 0.11), = 0.09, I = 43%], in HDL-C [MD = 0.02, 95% CI (-0.12, 0.16), = 0.07, I = 50%], in LDL-C [MD = 0.16, 95% CI (0.02, 0.29), = 0.17, I = 34%]. Based on the current evidence, acupoint catgut embedding is not significantly more effective than drugs in reducing hyperlipidemia. More randomized trials are needed to confirm this conclusion.
对于穴位埋线是否应广泛用于高脂血症的治疗，目前尚无共识。穴位埋线也未被纳入高脂血症治疗指南。本研究的目的有两个方面：1） 综述穴位埋线与高脂血症关系的最新研究进展，2） 对穴位埋线治疗高脂血症的效果进行荟萃分析。我们从 PubMed、Cochrane 图书馆、Embase CNKI、万方数据和 VIP 中提取研究进行荟萃分析，以确定评估穴位埋线对高脂血症疗效的随机对照试验（RCT），通过筛选、纳入、数据提取和质量评估进行研究。我们使用 Review Manager 5.3 软件进行荟萃分析。共纳入 9 项 RCT，涉及 500 多名 18 岁以上的成年人。与穴位埋线相比，药物在 TC [MD = -0.08，95%CI（-0.20，0.05）， = 0.41，I = 2%]、TG [MD = -0.04，95%CI（-0.20，0.11）， = 0.09，I = 43%]、HDL-C [MD = 0.02，95%CI（-0.12，0.16）， = 0.07，I = 50%]和 LDL-C [MD = 0.16，95%CI（0.02，0.29）， = 0.17，I = 34%]方面的疗效无显著差异。基于目前的证据，穴位埋线在降低高脂血症方面并不比药物更有效。需要更多的随机试验来证实这一结论。
