系统评价和 Meta 分析针灸和穴位埋线治疗腹型肥胖。
Systematic review and Meta-analysis of acupuncture and acupoint catgut embedding for the treatment of abdominal obesity.
机构信息
Diagnostics of Traditional Chinese Medicine, Beijing University of Traditional Chinese Medicine, Beijing 100029, China.
Internal encephalopathy of traditional Chinese medicine, Dongfang Hospital of Beijing University of Chinese Medicine, Beijing 100078, China.
出版信息
J Tradit Chin Med. 2022 Dec;42(6):848-857. doi: 10.19852/j.cnki.jtcm.2022.06.002.
OBJECTIVE
To systematically review and analyze the effect of acupuncture and acupoint catgut embedding in treatment of abdominal obesity to provide a more reasonable clinical treatment regimen.
METHODS
Ten databases were searched as of August 2022: the English databases PubMed, Embase, Cochrane Library, Web of Science, Wiley, and Scopus and the Chinese databases China National Knowledge Infrastructure Database, China Science and Technology Journal Database, Wanfang, and SinoMed/Chinese Biomedical Literature Database. Randomized controlled trials (RCTs) of acupuncture and acupoint catgut embedding as the main interventions to treat abdominal obesity were extracted. The investigators imported the citations into EndNote version X9.1 for deduplication, screening, extraction, and integration. The risk of bias in the included RCTs was assessed according to the Cochrane Handbook. RevMan 5.4 software was used to conduct a Meta-analysis of RCTs that met the inclusion criteria.
RESULTS
Thirteen RCTs (1069 patients) were included in this study, and the data of eleven RCTs (966 patients) were include in the Meta-analysis. The results showed that acupoint catgut embedding can significantly change the weight and waist circumference of patients with abdominal obesity when compared to sham acupuncture or no treatment [mean difference () = 2.32, 95% confidence interval () (1.88, 2.76), < 0.000 01], [ = 3.47, 95% (1.99, 4.94), < 0.000 01]. The change in hip circumference after acupuncture was also significant [ = 0.89, 95% (0.12, 1.66), = 0.02].
CONCLUSION
This study found that acupuncture and acupoint catgut embedding can effectively treat abdominal obesity, therefore, these interventions can be used as clinical supplements and alternative therapies. The diagnostic criteria of the existing studies and the intervention measures of the control group are not unified. It will be necessary to improve the clinical study protocols and expand the sample size to further validate the reliability of the results obtained of this study.
目的
系统评价和分析针灸和穴位埋线治疗腹型肥胖的效果，为临床提供更合理的治疗方案。
方法
检索 2022 年 8 月前的 10 个数据库：英文数据库 PubMed、Embase、Cochrane Library、Web of Science、Wiley、Scopus 和中文数据库中国知网、中国科技期刊数据库、万方、中国生物医学文献数据库。提取针灸和穴位埋线为主治疗腹型肥胖的随机对照试验（RCT）。研究者将引文导入 EndNote X9.1 进行去重、筛选、提取和整合。根据 Cochrane 手册评估纳入 RCT 的偏倚风险。使用 RevMan 5.4 软件对符合纳入标准的 RCT 进行 Meta 分析。
结果
纳入 13 项 RCT（1069 例患者），其中 11 项 RCT（966 例患者）的数据纳入 Meta 分析。结果显示，穴位埋线与假针刺或不治疗相比，能显著改变腹型肥胖患者的体重和腰围[均数差（MD）=2.32，95%置信区间（CI）（1.88，2.76），<0.000 01]，[MD=3.47，95%CI（1.99，4.94），<0.000 01]。针刺后臀围的变化也有统计学意义[MD=0.89，95%CI（0.12，1.66），=0.02]。
结论
本研究发现针灸和穴位埋线能有效治疗腹型肥胖，可作为临床补充和替代疗法。但现有研究的诊断标准和对照组的干预措施不统一，需要提高临床研究方案，扩大样本量，进一步验证本研究结果的可靠性。
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